Klee W A, Nirenberg M
Proc Natl Acad Sci U S A. 1974 Sep;71(9):3474-7. doi: 10.1073/pnas.71.9.3474.
A neuroblastoma x glioma hybrid cell line with well-developed neural properties was found that has high-affinity morphine receptors. The average cell contains approximately 3 x 10(6) receptors. In contrast, parent cells and other neuroblastoma or hybrid cell lines tested had few or no morphine receptors.
发现了一种具有高度发达神经特性且带有高亲和力吗啡受体的神经母细胞瘤与胶质瘤杂交细胞系。平均每个细胞含有约3×10⁶个受体。相比之下,所测试的亲代细胞以及其他神经母细胞瘤或杂交细胞系几乎没有或根本没有吗啡受体。