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在中等分辨率(7埃)下直接测定周围神经髓鞘的层状结构。

Direct determination of the lamellar structure of peripheral nerve myelin at moderate resolution (7A).

作者信息

Worthington C R, McIntosh T J

出版信息

Biophys J. 1974 Oct;14(10):703-29. doi: 10.1016/S0006-3495(74)85946-1.

DOI:10.1016/S0006-3495(74)85946-1
PMID:4547392
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1334569/
Abstract

Low-angle X-ray diffraction patterns have been recorded from normal nerve and nerve swollen in glycerol solutions. The new X-ray data have a resolution of 7 A. Direct methods of structure analysis which include deconvolution of the auto-correlation function and sampling theorem reconstructions have been used in the interpretation of the X-ray data. Phases have been assigned to the first 12 orders of diffraction from normal nerve. Fourier syntheses at a resolution of 7 A are described and an absolute electron density scale is derived. A possible molecular interpretation of the electron density profile is given.

摘要

已记录了来自正常神经和在甘油溶液中肿胀的神经的低角度X射线衍射图谱。新的X射线数据分辨率为7埃。在对X射线数据的解释中使用了包括自相关函数反卷积和采样定理重建在内的直接结构分析方法。已为正常神经的前12个衍射级分配了相位。描述了分辨率为7埃的傅里叶合成,并推导了绝对电子密度标度。给出了电子密度分布的一种可能的分子解释。

相似文献

1
Direct determination of the lamellar structure of peripheral nerve myelin at moderate resolution (7A).在中等分辨率(7埃)下直接测定周围神经髓鞘的层状结构。
Biophys J. 1974 Oct;14(10):703-29. doi: 10.1016/S0006-3495(74)85946-1.
2
Direct determination of the lamellar structure of peripheral nerve myelin at low resolution (17 A).在低分辨率(17埃)下直接测定周围神经髓鞘的层状结构。
Biophys J. 1974 May;14(5):363-86. doi: 10.1016/S0006-3495(74)85922-9.
3
The structure of the myelin sheath: Electron density distribution. Fourier plot.髓鞘的结构:电子密度分布。傅里叶图。
Neurosci Res Program Bull. 1971 Sep;9(4):535-9.
4
In vivo structure of frog sciatic nerve myelin membranes: an x-ray diffraction study at 13A resolution.青蛙坐骨神经髓鞘膜的体内结构:13埃分辨率的X射线衍射研究
J Neurosci Res. 1981;6(2):251-60. doi: 10.1002/jnr.490060212.
5
The effect of the repetitive propagation of action potentials on the structure of toad sciatic nerve myelin membranes: an x-ray diffraction study at 11 A resolution.动作电位的重复传播对蟾蜍坐骨神经髓鞘膜结构的影响:11埃分辨率的X射线衍射研究。
J Neurosci Res. 1980;5(6):611-20. doi: 10.1002/jnr.490050615.
6
[The structure of the myelin membrane of the frog sciatic nerve: in vivo determination by x-ray diffraction at 15 angstroms spatial resolution].[青蛙坐骨神经髓鞘膜的结构:在15埃空间分辨率下通过X射线衍射进行体内测定]
Acta Cient Venez. 1980;31(3):224-8.
7
The structure of the myelin sheath: Electron density distribution. Patterson plot.髓鞘的结构:电子密度分布。帕特森图。
Neurosci Res Program Bull. 1971 Sep;9(4):530-5.
8
[X-ray diffraction analysis of electron density distribution in myelin lamellar membranes of fresh nerve fibers].[新鲜神经纤维髓鞘板层膜中电子密度分布的X射线衍射分析]
Shinkei Kenkyu No Shimpo. 1972 Feb;16(1):29-33.
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Direct determination of the electron density profile of nerve myelin.神经髓磷脂电子密度分布的直接测定。
Nat New Biol. 1973 Sep 26;245(143):97-9. doi: 10.1038/newbio245097a0.
10
The structure of the myelin sheath. Electron density distribution. Phase problems.髓鞘的结构。电子密度分布。相位问题。
Neurosci Res Program Bull. 1971 Sep;9(4):526-30.

引用本文的文献

1
The diffuse scattering problem in membrane diffraction: a solution.膜衍射中的漫散射问题:一种解决方案。
Biophys J. 1986 Jan;49(1):98-101. doi: 10.1016/S0006-3495(86)83608-6.
2
Membrane structure in isolated and intact myelins.分离的和完整的髓磷脂中的膜结构。
Biophys J. 1989 Jul;56(1):129-37. doi: 10.1016/S0006-3495(89)82658-X.
3
Phase determination of x-ray reflections for membrane-type systems with constant fluid density.具有恒定流体密度的膜型系统的X射线反射相测定
Biophys J. 1976 May;16(5):503-16. doi: 10.1016/S0006-3495(76)85705-0.
4
Myelin x-ray patterns reconciled.髓磷脂X射线图谱已得到调和。
Biophys J. 1976 May;16(5):491-501. doi: 10.1016/S0006-3495(76)85704-9.
5
The determination of the electron density profile of the human erythrocyte ghost membrane by small-angle x-ray diffraction.通过小角X射线衍射测定人红细胞血影膜的电子密度分布
Biophys J. 1977 Aug;19(2):141-61. doi: 10.1016/S0006-3495(77)85576-8.
6
Structure determination of asymmetric membrane profiles using an iterative Fourier method.使用迭代傅里叶方法确定不对称膜轮廓的结构
Biophys J. 1979 Mar;25(3):495-512. doi: 10.1016/S0006-3495(79)85319-9.
7
Liquid diffraction analysis of the model membrane system. Egg lecithin + myelin protein (N-2).模型膜系统的液体衍射分析。卵磷脂+髓磷脂蛋白(N-2)。
Biophys J. 1979 Apr;26(1):23-42. doi: 10.1016/S0006-3495(79)85232-7.

本文引用的文献

1
THE DETERMINATION OF THE FOURIER TRANSFORM OF THE MYELIN LAYER FROM A STUDY OF SWELLING PHENOMENA.通过对肿胀现象的研究测定髓鞘层的傅里叶变换
J Mol Biol. 1963 Dec;7:672-82. doi: 10.1016/s0022-2836(63)80115-1.
2
X-RAY DIFFRACTION PATTERN OF NERVE MYELIN: A METHOD FOR DETERMINING THE PHASES.神经髓磷脂的X射线衍射图谱:一种确定相位的方法。
Science. 1963 Nov 29;142(3596):1173-4. doi: 10.1126/science.142.3596.1173.
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A structural analysis of nerve myelin.神经髓鞘的结构分析
Biophys J. 1969 Jul;9(7):970-90. doi: 10.1016/S0006-3495(69)86431-3.
4
Low-angle x-ray diffraction patterns from a variety of myelinated nerves.来自多种有髓神经的低角度X射线衍射图谱。
Biochim Biophys Acta. 1969 Apr;173(3):419-26. doi: 10.1016/0005-2736(69)90006-6.
5
The interpretation of low-angle X-ray data from planar and concentric multilayered structures. The use of one-dimensional electron density strip models.平面和同心多层结构低角度X射线数据的解释。一维电子密度条模型的应用。
Biophys J. 1969 Feb;9(2):222-34. doi: 10.1016/S0006-3495(69)86381-2.
6
The maturation of human white matter myelin. Fractionation of the myelin membrane proteins.人类白质髓鞘的成熟。髓鞘膜蛋白的分级分离。
Biochemistry. 1968 Dec;7(12):4455-65. doi: 10.1021/bi00852a042.
7
Structure of the nerve myelin membrane: proof of the low-resolution profile.神经髓鞘膜的结构:低分辨率轮廓的证据。
J Mol Biol. 1971 Feb 28;56(1):35-52. doi: 10.1016/0022-2836(71)90082-9.
8
Myelin membrane structure at 10 A resolution.10埃分辨率下的髓鞘膜结构。
Nat New Biol. 1971 May 12;231(19):46-52. doi: 10.1038/newbio231046a0.
9
Structure of oriented lipid bilayers.定向脂质双层的结构。
Nat New Biol. 1971 Mar 17;230(11):69-72. doi: 10.1038/newbio230069a0.
10
Structural parameters of nerve myelin.神经髓鞘的结构参数
Proc Natl Acad Sci U S A. 1969 Jul;63(3):604-11. doi: 10.1073/pnas.63.3.604.