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1
Genetic correlation of a mouse light chain variable region marker with a thymocyte surface antigen.小鼠轻链可变区标记与胸腺细胞表面抗原的遗传相关性。
J Exp Med. 1974 Nov 1;140(5):1432-7. doi: 10.1084/jem.140.5.1432.
2
The IB-peptide marker and the Ly-3 surface alloantigen: structural studies of a V kappa-region polymorphism and a T-cell marker determined by linked genes.IB肽标志物与Ly-3表面同种异体抗原:由连锁基因决定的Vκ区域多态性和T细胞标志物的结构研究
Cold Spring Harb Symp Quant Biol. 1977;41 Pt 2:805-15. doi: 10.1101/sqb.1977.041.01.091.
3
Segregation at a locus determining an immunoglobulin genetic marker for the light chain variable region affects inheritance of expression of an idiotype.决定轻链可变区免疫球蛋白遗传标记的基因座上的分离影响独特型表达的遗传。
Proc Natl Acad Sci U S A. 1977 Oct;74(10):4600-4. doi: 10.1073/pnas.74.10.4600.
4
Assignment of the Ly-6--Ril-1--Sis--H-30--Pol-5/Xmmv-72--Ins-3--Krt-1--Int-1 --Gdc-1 region to mouse chromosome 15.将Ly-6--Ril-1--Sis--H-30--Pol-5/Xmmv-72--Ins-3--Krt-1--Int-1 --Gdc-1区域定位到小鼠第15号染色体上。
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5
Definition of new alloantigens encoded by genes in the Ly-6 complex.Ly-6复合体中基因编码的新同种异体抗原的定义。
Immunogenetics. 1984;20(1):57-69. doi: 10.1007/BF00373447.
6
Ef2: a new LY-3-linked light-chain marker expressed in normal mouse serum immunoglobulin.Ef2:一种在正常小鼠血清免疫球蛋白中表达的新型LY-3连接轻链标志物。
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7
Antigen-specific T-cell factor in cell cooperation: physical properties and mapping in the left-hand (K) half of H-2.细胞协作中的抗原特异性T细胞因子:物理性质及在H-2左手(K)半区的定位
J Exp Med. 1974 Dec 1;140(6):1579-87. doi: 10.1084/jem.140.6.1579.
8
A new lymphocyte surface antigen (Ly-m31) controlled by a gene closely linked to the Akp-2 locus on mouse chromosome 4.一种新的淋巴细胞表面抗原(Ly-m31),由与小鼠4号染色体上Akp-2基因座紧密连锁的基因所控制。
Immunogenetics. 1984;20(5):589-92. doi: 10.1007/BF00364361.
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The Ly-3 antigens on mouse thymocytes: immune precipitation and molecular weight characterization.小鼠胸腺细胞上的Ly-3抗原:免疫沉淀及分子量特性分析
J Exp Med. 1976 Aug 1;144(2):476-93. doi: 10.1084/jem.144.2.476.
10
Studies of the mouse Ly-6 alloantigen system. II. Complexities of the Ly-6 region.小鼠Ly-6同种异体抗原系统的研究。II. Ly-6区域的复杂性。
Immunogenetics. 1984;20(1):47-56. doi: 10.1007/BF00373446.

引用本文的文献

1
Construction and properties of new Lyt-congenic strains and anti-Lyt-2.2 and anti-Lyt-3.1 monoclonal antibodies.新型 Lyt 同基因株系的构建与特性,以及抗 Lyt-2.2 和抗 Lyt-3.1 单克隆抗体。
Immunogenetics. 1980;10(6):545-55. doi: 10.1007/BF01572589.
2
Linkage between low-density lipoprotein and igk light-chain genes in rabbits.兔低密度脂蛋白与 igk 轻链基因的连锁关系。
Immunogenetics. 1978 Dec;7(1):117-23. doi: 10.1007/BF01843996.
3
Characterization of the mouse CD8 beta chain-encoding gene promoter region.小鼠CD8β链编码基因启动子区域的特征分析。
Immunogenetics. 1996;44(5):358-65. doi: 10.1007/BF02602780.
4
Effects of Lyt antibodies on T-cell functions: augmentation by anti-Lyt-1 as opposed to inhibition by anti-Lyt-2.Lyt抗体对T细胞功能的影响:抗Lyt-1起增强作用,而抗Lyt-2起抑制作用。
Proc Natl Acad Sci U S A. 1981 Feb;78(2):1148-51. doi: 10.1073/pnas.78.2.1148.
5
Blocking effect of lyt-2 antibodies on T cell functions.Lyt-2抗体对T细胞功能的阻断作用。
J Exp Med. 1980 Sep 1;152(3):674-87. doi: 10.1084/jem.152.3.674.
6
Alloantigen-induced T-cell proliferation: Lyt phenotype of responding cells and blocking of proliferation by Lyt antisera.同种异体抗原诱导的T细胞增殖:应答细胞的Lyt表型及Lyt抗血清对增殖的阻断作用。
Proc Natl Acad Sci U S A. 1980 May;77(5):2890-4. doi: 10.1073/pnas.77.5.2890.
7
Role and strain distribution of genes controlling light chains needed for the expression of an intrastrain cross-reactive idiotype.控制菌株内交叉反应独特型表达所需轻链的基因的作用及菌株分布
Immunogenetics. 1981;14(1-2):85-99. doi: 10.1007/BF00344302.
8
Unique V kappa group associated with two mouse L chain genetic markers.与两个小鼠轻链遗传标记相关的独特Vκ基因群
Proc Natl Acad Sci U S A. 1981 Jan;78(1):559-63. doi: 10.1073/pnas.78.1.559.
9
Thymus-dependent membrane antigens in man: inhibition of cell-mediated lympholysis by monoclonal antibodies to TH2 antigen.人类中依赖胸腺的膜抗原:抗TH2抗原单克隆抗体对细胞介导的淋巴细胞溶解的抑制作用
Proc Natl Acad Sci U S A. 1981 Jan;78(1):544-8. doi: 10.1073/pnas.78.1.544.
10
A major group of mouse kappa chains controlled by the chromosome 6 locus, IgK-Ef2.由6号染色体位点IgK-Ef2控制的一大组小鼠κ链。
J Exp Med. 1980 Sep 1;152(3):555-64. doi: 10.1084/jem.152.3.555.

本文引用的文献

1
Ly-C: a third locus specifying alloantigens expressed only on thymocytes and lymphocytes.Ly-C:第三个基因座,它决定了仅在胸腺细胞和淋巴细胞上表达的同种异体抗原。
Transplantation. 1971 Mar;11(3):351-3.
2
A genetic marker in the variable region of light chains of mouse immunoglobulins.小鼠免疫球蛋白轻链可变区中的一种遗传标记。
Proc Natl Acad Sci U S A. 1970 Nov;67(3):1192-9. doi: 10.1073/pnas.67.3.1192.
3
An approach to the mapping of antigens on the cell surface.一种绘制细胞表面抗原图谱的方法。
Proc Natl Acad Sci U S A. 1968 Jul;60(3):886-93. doi: 10.1073/pnas.60.3.886.
4
Genetic linkage relationships of loci specifying differentiation alloantigens in the mouse.小鼠中决定分化同种异体抗原的基因座的遗传连锁关系。
Transplantation. 1972 Mar;13(3):239-43. doi: 10.1097/00007890-197203000-00007.
5
Antibody diversity.抗体多样性
Annu Rev Biochem. 1971;40:969-1012. doi: 10.1146/annurev.bi.40.070171.004541.
6
List of congenic lines of mice. I. Lines with differences at alloantigen loci.小鼠同类系列表。I. 在同种异体抗原位点存在差异的品系。
Transplantation. 1973 Jan;15(1):137-53. doi: 10.1097/00007890-197301000-00021.
7
Genetic control of the immune response. Mapping of the Ir-1 locus.免疫反应的遗传控制。Ir-1基因座的定位。
J Exp Med. 1972 Jun 1;135(6):1259-78. doi: 10.1084/jem.135.6.1259.
8
Ly-A and Ly-B: two systems of lymphocyte isoantigens in the mouse.Ly - A和Ly - B:小鼠淋巴细胞同种抗原的两个系统。
Proc R Soc Lond B Biol Sci. 1968 Jun 11;170(1019):175-93. doi: 10.1098/rspb.1968.0032.
9
Host-gene control of C-type RNA tumor virus: inheritance of the group-specific antigen of murine leukemia virus.C型RNA肿瘤病毒的宿主基因控制:小鼠白血病病毒群特异性抗原的遗传
Proc Natl Acad Sci U S A. 1971 Dec;68(12):3190-4. doi: 10.1073/pnas.68.12.3190.
10
The genetic control of immunoglobulin synthesis.免疫球蛋白合成的遗传控制。
Annu Rev Genet. 1972;6:1-46. doi: 10.1146/annurev.ge.06.120172.000245.

小鼠轻链可变区标记与胸腺细胞表面抗原的遗传相关性。

Genetic correlation of a mouse light chain variable region marker with a thymocyte surface antigen.

作者信息

Gottlieb P D

出版信息

J Exp Med. 1974 Nov 1;140(5):1432-7. doi: 10.1084/jem.140.5.1432.

DOI:10.1084/jem.140.5.1432
PMID:4547628
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2139733/
Abstract

The inbred and congenic strain distribution of the I(H)-peptide marker in the variable region of mouse immunoglobulin light chains has been compared with other known genetic markers. A positive correlation was noted between the I(H)-peptide marker and expression of the Ly-3.1 thymocyte cell surface antigen. This suggests that the locus responsible for I(H)-peptide expression is genetically linked to the Ly-2 and Ly-3 loci in linkage group XI on chromsome 6 of the mouse.

摘要

已将小鼠免疫球蛋白轻链可变区中I(H)肽标记的近交系和同源系分布与其他已知遗传标记进行了比较。发现I(H)肽标记与Ly-3.1胸腺细胞表面抗原的表达之间存在正相关。这表明负责I(H)肽表达的基因座在遗传上与小鼠6号染色体连锁群XI中的Ly-2和Ly-3基因座相关。