钙化醇作为灭鼠剂的一些特性。
Some properties of calciferol as a rodenticide.
作者信息
Greaves J H, Redfern R, King R E
出版信息
J Hyg (Lond). 1974 Dec;73(3):341-51. doi: 10.1017/s0022172400042686.
The potentiality of calciferol (alone and combined with warfarin) for the control of commensal rats and mice has been examined in the laboratory. Nearly all animals fed on 0.1% calciferol for 2 days died. Though illness usually reduced food intake after the first 24 hr. there was no sign of aversion to the poison at 0.1% - which is considered to be the lowest concentration suitable for use against Rattus norvegicus, R. rattus and Mus musculus in the field. There was some indication that resistance to warfarin in R. norvegicus may be correlated with susceptibility to calciferol. Toxicity tests with calciferol combined with warfarin indicated an additive effect between the compounds. No evidence for synergism was found however, although elsewhere there is some evidence for this.
在实验室中研究了钙化醇（单独使用以及与华法林联合使用）控制家栖大鼠和小鼠的潜力。几乎所有食用0.1%钙化醇2天的动物都死亡了。尽管在前24小时病畜通常会减少食物摄入量，但在0.1%的浓度下没有厌恶该毒药的迹象——这被认为是在野外用于防治褐家鼠、黑家鼠和小家鼠的最低适用浓度。有迹象表明，褐家鼠对华法林的抗性可能与对钙化醇的易感性相关。钙化醇与华法林联合进行的毒性试验表明，两种化合物之间存在相加作用。然而，未发现协同作用的证据，尽管在其他地方有一些这方面的证据。
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