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在缺乏脱氧核糖核酸聚合酶I的大肠杆菌菌株中,包含uvrB的缺失的条件致死性。

Conditional lethality of deletions which include uvrB in strains of Escherichia coli lacking deoxyribonucleic acid polymerase I.

作者信息

Shizuya H, Dykhuizen D

出版信息

J Bacteriol. 1972 Nov;112(2):676-81. doi: 10.1128/jb.112.2.676-681.1972.

Abstract

Deletions of the uvrB gene were not obtained in polA1 strains of Escherichia coli either by selecting for spontaneous deletions or by transduction from strains carrying such deletions. A strain forming a temperature-sensitive deoxyribonucleic acid polymerase I and carrying a deletion of the uvrB gene is inviable at the nonpermissive temperature.

摘要

在大肠杆菌的polA1菌株中,无论是通过选择自发缺失还是从携带此类缺失的菌株进行转导,都无法获得uvrB基因的缺失。一个形成温度敏感型脱氧核糖核酸聚合酶I并携带uvrB基因缺失的菌株在非允许温度下无法存活。

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