Hanna E E, Watson D W
Infect Immun. 1973 Jun;7(6):1009-11. doi: 10.1128/iai.7.6.1009-1011.1973.
Streptococcal pyrogenic exotoxin (SPE) was shown previously to be a potent immunosuppressant. This paper presents data documenting that immunosuppression frequently was followed by elevated antibody and plaque-forming cell levels as noted in our earlier report. The data are interpreted as a differential effect of SPE upon suppressor T cells and secreting B cells.
先前已证明链球菌热原性外毒素(SPE)是一种强效免疫抑制剂。本文提供的数据表明,如我们之前的报告所述,免疫抑制之后常常会出现抗体和噬斑形成细胞水平升高的情况。这些数据被解释为SPE对抑制性T细胞和分泌性B细胞的差异性作用。