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Expression of H-2 and Moloney leukemia virus-determined cell-surface antigens in synchronized cultures of a mouse cell line.H-2和莫洛尼白血病病毒决定的细胞表面抗原在小鼠细胞系同步培养物中的表达。
Proc Natl Acad Sci U S A. 1971 Mar;68(3):566-9. doi: 10.1073/pnas.68.3.566.
2
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Springer Semin Immunopathol. 1979;2(3):261-283. doi: 10.1007/BF00198720.
2
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The heterogenization of tumour cells with tuberculin. II. Studies of the antigenicity of tuberculin-heterogenized murine tumour cells in syngeneic BCG positive and BCG negative mice.肿瘤细胞与结核菌素的异质化。II. 结核菌素异质化的小鼠肿瘤细胞在同基因卡介苗阳性和阴性小鼠中的抗原性研究。
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9
Cytotoxic T lymphocytes in DBA/2 mice harboring L5178Y cells in a tumor-dormant state.处于肿瘤休眠状态且携带有L5178Y细胞的DBA/2小鼠中的细胞毒性T淋巴细胞。
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10
Inhibition or enhancement of immunological injury of virus-infected cells.病毒感染细胞免疫损伤的抑制或增强。
Proc Natl Acad Sci U S A. 1971 Dec;68(12):3073-7. doi: 10.1073/pnas.68.12.3073.

本文引用的文献

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Infection of an established mouse bone marrow cell line (JLS-V9) with Rauscher and Moloney murine leukemia viruses.用劳斯氏和莫洛尼氏小鼠白血病病毒感染已建立的小鼠骨髓细胞系(JLS-V9)。
Cancer Res. 1967 Sep;27(9):1672-7.
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Variable behaviour of blood group H on HeLa cell populations synchronized with thymidine.与胸腺嘧啶核苷同步化的HeLa细胞群体上血型H的可变行为。
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Changes in lactate dehydrogenase and esterase-specific activities, isozymic patterns, and cellular distribution during the growth cycle of PK cells in vitro.体外培养的PK细胞生长周期中乳酸脱氢酶和酯酶的比活性、同工酶谱及细胞分布的变化。
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5
Immunoglobulin production in synchronized cultures of human hematopoietic cell lines. I. Variation of cellular immunoglobulin level with the generation cycle.人造血细胞系同步培养物中的免疫球蛋白产生。I. 细胞免疫球蛋白水平随细胞世代周期的变化。
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H-2和莫洛尼白血病病毒决定的细胞表面抗原在小鼠细胞系同步培养物中的表达。

Expression of H-2 and Moloney leukemia virus-determined cell-surface antigens in synchronized cultures of a mouse cell line.

作者信息

Cikes M, Friberg S

出版信息

Proc Natl Acad Sci U S A. 1971 Mar;68(3):566-9. doi: 10.1073/pnas.68.3.566.

DOI:10.1073/pnas.68.3.566
PMID:5276763
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC388990/
Abstract

A mouse cell line derived from bone marrow (JLS-V9) was infected in vitro with Moloney leukemia virus. After the cell-surface antigens specified by this virus appeared, cells were synchronized in mitosis by a short treatment with colcemid. The expression of H-2- and virus-determined surface antigens was monitored during one cell cycle by an indirect membrane-immunofluorescence test. The highest proportion of antigen-positive cells was found during the G1 period; the proportion dropped as the cells entered the S period, and remained low until they entered the G1 period of the next cycle. The H-2- and virus-determined surface antigens were temporally coexpressed.

摘要

一种源自骨髓的小鼠细胞系(JLS-V9)在体外被莫洛尼白血病病毒感染。在这种病毒所特有的细胞表面抗原出现后,通过用秋水仙酰胺进行短暂处理使细胞在有丝分裂中同步化。通过间接膜免疫荧光试验在一个细胞周期内监测H-2和病毒决定的表面抗原的表达。在G1期发现抗原阳性细胞的比例最高;当细胞进入S期时该比例下降,并一直保持较低水平直到进入下一个周期的G1期。H-2和病毒决定的表面抗原在时间上是共表达的。