支原体相关免疫抑制：对兔针对常见抗原的血凝素反应的影响。
Mycoplasma-associated immunosuppression: effect on hemagglutinin response to common antigens in rabbits.
作者信息
Bergquist L M, Lau B H, Winter C E
出版信息
Infect Immun. 1974 Feb;9(2):410-5. doi: 10.1128/iai.9.2.410-415.1974.
Abstract
A Mycoplasma-associated immunosuppression of the primary and secondary hemagglutinin response to a common gram-negative antigen of Escherichia coli (014) was demonstrated in the rabbit when preincubated mixtures of common gram-negative antigen and Mycoplasma arthritidis membranes were injected intravenously. A similar immunosuppression was demonstrated only for the secondary hemagglutinin response to a common gram-positive antigen of Staphylococcus aureus when preincubated mixtures of common gram-positive antigen and M. arthritidis membranes were employed as immunizing materials. The immunosuppressive effect occurred with small quantities of M. arthritidis membranes and appeared not to be limited to the host in which arthritogenic properties of the organism were manifested.
摘要
当静脉注射普通革兰氏阴性抗原与关节炎支原体膜的预孵育混合物时，在兔体内证实了支原体对针对大肠杆菌（O14）常见革兰氏阴性抗原的初次和二次血凝素反应的免疫抑制作用。当使用普通革兰氏阳性抗原与关节炎支原体膜的预孵育混合物作为免疫材料时，仅对针对金黄色葡萄球菌常见革兰氏阳性抗原的二次血凝素反应表现出类似的免疫抑制作用。少量的关节炎支原体膜即可产生免疫抑制作用，且这种作用似乎并不局限于该生物体表现出致关节炎特性的宿主。
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