指数生长的微生物培养物中不同基因的相对数量。
The relative numbers of different genes in exponential microbial cultures.
作者信息
Painter P R
出版信息
Genetics. 1974 Mar;76(3):401-10. doi: 10.1093/genetics/76.3.401.
Abstract
It is shown that the results of the marker frequency analysis of Sueoka and Yoshikawa (1965) can be derived as very good approximations from a model where the rigid assumptions of their analysis are relaxed to take into account statistical variations in the timing of cell events. It is further shown that the expression for the amount of DNA per cell can be approximated by an elementary exponential function of the growth rate, and this result facilitates genetic mapping by DNA hybridization techniques. An analysis of recent data on gene frequencies in Escherichia coli corroborates a model of symmetric, bidirectional chromosome replication with a replication time of approximately thirty minutes.
摘要
结果表明，末冈和吉川（1965年）的标记频率分析结果可以从一个模型中非常好地近似得出，该模型放宽了他们分析中的严格假设，以考虑细胞事件发生时间的统计变化。进一步表明，每个细胞的DNA量的表达式可以用生长速率的一个基本指数函数来近似，这一结果有助于通过DNA杂交技术进行基因定位。对大肠杆菌基因频率的最新数据的分析证实了一个对称、双向染色体复制模型，其复制时间约为30分钟。
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2
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Proc Natl Acad Sci U S A. 1963 Apr;49(4):559-66. doi: 10.1073/pnas.49.4.559.
3
Thymine deficiency and the normal DNA replication cycle. I.胸腺嘧啶缺乏与正常DNA复制周期。I.
J Mol Biol. 1961 Apr;3:144-55. doi: 10.1016/s0022-2836(61)80041-7.
4
Dependency on medium and temperature of cell size and chemical composition during balanced grown of Salmonella typhimurium.鼠伤寒沙门氏菌平衡生长期间细胞大小和化学成分对培养基及温度的依赖性。
J Gen Microbiol. 1958 Dec;19(3):592-606. doi: 10.1099/00221287-19-3-592.
5
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