Vorkunova G K, Dotsenko G N, Bukrinskaia A G, Zhdanov V M
Vopr Virusol. 1979 May-Jun(3):217-20.
The "return" of influenza A (HINI) virus after 20 years of absence raised the question of the sources and mechanisms of emergence of epidemic influenza viruses and, particularly, of a new HINI virus (A/USSR/90/77). Two alternative hypotheses answer this question differently: the new HINI virus is the progeny of old HINI viruses retained in the human population or is a newly arising recombinant between numerous human and animal influenza viruses circulation in the biosphere. For the acceptance of one or the other hypothesis further accumulation of facts is required and, first of all, comparative investigations of RNAs and proteins of various influenza viruses. This paper presents the results of comparative studies of RNAs and proteins of old and new influenza A (HINI) viruses.
甲型H1N1流感病毒在消失20年后的“重现”引发了关于流行性流感病毒出现的来源和机制的问题，尤其是一种新型H1N1病毒（A/USSR/90/77）出现的来源和机制问题。两种不同的假设对这一问题给出了不同的答案：新型H1N1病毒是留存于人群中的旧有H1N1病毒的后代，或者是生物圈中大量人类和动物流感病毒之间新出现的重组体。为了采信其中一种假设，需要进一步积累事实，首先是对各种流感病毒的RNA和蛋白质进行比较研究。本文呈现了对新旧甲型H1N1流感病毒的RNA和蛋白质进行比较研究的结果。
