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[灵菌红素刺激大鼠急性中毒性肝炎的发展特征]

[Characteristics of the development of acute toxic hepatitis in rats stimulated with prodigiozan].

作者信息

Maianskiĭ D N, Kutina S N

出版信息

Biull Eksp Biol Med. 1979 Jun;87(6):622-4.

PMID:465705
Abstract

Acute toxic hepatitis was induced in Wistar rats by means of a single injection of 40% CCl4 on a peach-kernell oil base (0.2 ml/100 g body weight). Under conditions of stimulation with the bacterial polysaccharide prodigiosan, the resistance of hepatocytes to CCl4 sharply increased, which was shown by diminished severity of hepatic parenchyma destruction.

摘要

通过在桃仁油基质中单次注射40%四氯化碳(0.2毫升/100克体重)诱导Wistar大鼠发生急性中毒性肝炎。在用细菌多糖灵菌红素刺激的条件下,肝细胞对四氯化碳的抵抗力急剧增加,这表现为肝实质破坏的严重程度减轻。

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1
[Characteristics of the development of acute toxic hepatitis in rats stimulated with prodigiozan].[灵菌红素刺激大鼠急性中毒性肝炎的发展特征]
Biull Eksp Biol Med. 1979 Jun;87(6):622-4.
2
[CCl4 resistance of the liver after endotoxin and prodigiozan stimulation].
Patol Fiziol Eksp Ter. 1985 Nov-Dec(6):42-5.
3
[Increased hepatocyte resistance to CC14 following the stimulation of rats with a bacterial polysaccharide].[用一种细菌多糖刺激大鼠后肝细胞对四氯化碳的抵抗力增强]
Farmakol Toksikol. 1985 Jul-Aug;48(4):96-9.
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Liver resistance to CCl(4)-induced injury after stimulation of macrophages with various preparations.用各种制剂刺激巨噬细胞后肝脏对四氯化碳诱导损伤的抗性。
Bull Exp Biol Med. 2000 Jun;129(6):524-6. doi: 10.1007/BF02434865.
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