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[灵菌红素刺激大鼠急性中毒性肝炎的发展特征]

[Characteristics of the development of acute toxic hepatitis in rats stimulated with prodigiozan].

作者信息

Maianskiĭ D N, Kutina S N

出版信息

Biull Eksp Biol Med. 1979 Jun;87(6):622-4.

PMID:465705
Abstract

Acute toxic hepatitis was induced in Wistar rats by means of a single injection of 40% CCl4 on a peach-kernell oil base (0.2 ml/100 g body weight). Under conditions of stimulation with the bacterial polysaccharide prodigiosan, the resistance of hepatocytes to CCl4 sharply increased, which was shown by diminished severity of hepatic parenchyma destruction.

摘要

通过在桃仁油基质中单次注射40%四氯化碳(0.2毫升/100克体重)诱导Wistar大鼠发生急性中毒性肝炎。在用细菌多糖灵菌红素刺激的条件下,肝细胞对四氯化碳的抵抗力急剧增加,这表现为肝实质破坏的严重程度减轻。

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