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烟曲霉和申克孢子丝菌分离株对两性霉素B的体外敏感性

In vitro susceptibility of isolates of Aspergillus fumigatus and Sporothrix schenckii to amphotericin B.

作者信息

Brandsberg J W, French M E

出版信息

Antimicrob Agents Chemother. 1972 Nov;2(5):402-4. doi: 10.1128/AAC.2.5.402.

Abstract

The in vitro susceptibility of 21 isolates of Aspergillus fumigatus and 12 isolates of Sporothrix schenckii to amphotericin B was determined. The minimal inhibitory concentration (MIC) for the A. fumigatus isolates ranged from 0.14 to 0.6 mug of drug per ml. The mean MIC for the 21 isolates was 0.33 mug per ml. The MIC for the 12 S. schenckii isolates ranged from 0.68 to 2.12 mug of drug per ml, with a mean MIC of 1.38 mug per ml.

摘要

测定了21株烟曲霉和12株申克孢子丝菌对两性霉素B的体外敏感性。烟曲霉分离株的最低抑菌浓度(MIC)范围为每毫升0.14至0.6微克药物。21株分离株的平均MIC为每毫升0.33微克。12株申克孢子丝菌分离株的MIC范围为每毫升0.68至2.12微克药物,平均MIC为每毫升1.38微克。

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本文引用的文献

1
TREATMENT OF PULMONARY ASPERGILLOMA WITH AMPHOTERICIN B.两性霉素B治疗肺曲菌球
Arch Intern Med. 1965 May;115:598-601. doi: 10.1001/archinte.1960.03860170080017.
4
Susceptibility of Cryptococcus neoformans to amphotericin B.
Antimicrob Agents Chemother (Bethesda). 1966;6:405-10. doi: 10.1128/AAC.6.4.405.
5
Resistance to various inhibitors in Aspergillus nidulans.构巢曲霉对多种抑制剂的抗性。
J Gen Microbiol. 1965 Aug;40(2):273-81. doi: 10.1099/00221287-40-2-273.
9
Amphotericin B serum concentrations during therapy.治疗期间两性霉素B的血清浓度。
Appl Microbiol. 1970 Jun;19(6):955-9. doi: 10.1128/am.19.6.955-959.1970.
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