校正钙的矛盾解决了吗？静脉淤滞或心肌梗死后血浆白蛋白变化对血浆总钙的不同影响。
Adjusted calcium conflict resolved? Differing effects on plasma total calcium of changes in plasma albumin after venous stasis or myocardial infarction.
作者信息
Walker B E, Payne R B
出版信息
J Clin Pathol. 1979 May;32(5):488-91. doi: 10.1136/jcp.32.5.488.
Abstract
Others have challenged the concept of adjusting total plasma calcium for albumin concentration on the grounds that after the application of a tourniquet the increase in calcium for a given increase in albumin differs significantly between normal individuals. We have confirmed this finding. In contrast, we have found that after myocardial infarction the fall in calcium for a given fall in albumin does not differ significantly between patients. Thus the adjustment of calcium for albumin using a single equation remains valid in patients with changes in albumin due to disease. We recommend that for consistent results blood should be taken with the minimum of venous stasis even though the patient's calcium is to be adjusted for albumin.
摘要
其他人对根据白蛋白浓度调整总血浆钙的概念提出了质疑，理由是在使用止血带后，正常个体之间因白蛋白给定增加而导致的钙增加存在显著差异。我们已经证实了这一发现。相比之下，我们发现心肌梗死后，患者之间因白蛋白给定下降而导致的钙下降并无显著差异。因此，在因疾病导致白蛋白发生变化的患者中，使用单一公式根据白蛋白调整钙仍然是有效的。我们建议，为了获得一致的结果，即使要根据白蛋白对患者的钙进行调整，采血时也应尽量减少静脉淤血。
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