气相色谱法测定尿中马尿酸和间甲基马尿酸
Measurement of urinary hippuric and m-methylhippuric acids by gas chromatography.
作者信息
Buchet J P, Lauwerys R R
出版信息
Br J Ind Med. 1973 Apr;30(2):125-8. doi: 10.1136/oem.30.2.125.
Abstract
125-128. A gas chromatographic method for the determination of hippuric and m-methylhippuric acids in urine is described. A known amount of heptadecanoic acid (internal standard) is added to the urine before its extraction with ethyl acetate. After evaporation of the solvent, the acids are methylated with diazomethane. The residue is taken up in methanol and injected into the gas chromatograph. The ratio of the height of the hippuric or m-methylhippuric acid peak to the height of the heptadecanoic acid peak is calculated and by reference to a calibration curve prepared in the same conditions the urine concentration of the two acids is determined.
摘要
125 - 128. 描述了一种用于测定尿液中马尿酸和间甲基马尿酸的气相色谱法。在尿液用乙酸乙酯萃取之前，加入已知量的十七烷酸（内标）。溶剂蒸发后，酸用重氮甲烷进行甲基化。残留物用甲醇溶解并注入气相色谱仪。计算马尿酸或间甲基马尿酸峰高与十七烷酸峰高的比值，并参照在相同条件下制备的校准曲线确定两种酸在尿液中的浓度。
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本文引用的文献
1
2
The quantitative determination of hippuric acid.马尿酸的定量测定。
J Biol Chem. 1954 Feb;206(2):695-8.
3
Significance of urinary hippuric acid determination as an index of toluene exposure.尿马尿酸测定作为甲苯暴露指标的意义。
Br J Ind Med. 1969 Jul;26(3):244-6. doi: 10.1136/oem.26.3.244.
4
Urinary hippuric acid excretion as an index of toluene exposure.尿马尿酸排泄作为甲苯暴露的指标。
Am Ind Hyg Assoc J. 1967 Mar-Apr;28(2):129-34. doi: 10.1080/00028896709342496.
5
Quantitative determination in urine of hippuric acid and m- or p-methylhippuric acid, metabolites of toluene and m- or p-xylene.尿液中马尿酸以及甲苯和间二甲苯或对二甲苯的代谢产物间甲基马尿酸或对甲基马尿酸的定量测定。
Br J Ind Med. 1969 Oct;26(4):330-4. doi: 10.1136/oem.26.4.330.
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