Bruun J N, Solberg C O
Br Med J. 1973 Jun 9;2(5866):580-2. doi: 10.1136/bmj.2.5866.580.
The influence of hexachlorophane disinfection on the bacterial hand flora of hospital personnel has been examined. Hexachlorophane effectively reduced the total number of bacteria and the staphylococcal carriage. Gram-negative bacilli were isolated from 18.8% of the personnel, and 13% of the carriers continued to carry Gram-negative bacilli for more than six months. The carrier rate was significantly higher among those using hexachlorophane detergents (20.8%) than among those using plain soap (14.1%). Prolonged hand carriage of Gram-negative bacilli was often associated with skin irritation, especially of the nailfolds. Hand carriage may be an important source of Gram-negative infections in hospital, and the increase in these infections may partly be due to extensive use of hexachlorophane preparations.
已对六氯酚消毒对医院工作人员手部细菌菌群的影响进行了研究。六氯酚能有效减少细菌总数和葡萄球菌携带情况。18.8%的工作人员分离出革兰氏阴性杆菌,13%的携带者持续携带革兰氏阴性杆菌超过六个月。使用六氯酚洗涤剂的人员(20.8%)的携带率显著高于使用普通肥皂的人员(14.1%)。革兰氏阴性杆菌的长期手部携带通常与皮肤刺激有关,尤其是甲沟处。手部携带可能是医院革兰氏阴性感染的重要来源,这些感染的增加可能部分归因于六氯酚制剂的广泛使用。