Sladen G E, Kumar P J
Br Med J. 1973 Jul 28;3(5873):223-6. doi: 10.1136/bmj.3.5873.223.
In a retrospective survey the results of a D-xylose absorption test have been assessed in relation to jejunal morphology and final diagnosis in 152 adult patients with various types of gastrointestinal disease. Neither urine excretion rates nor serum concentrations alone provide an adequate separation between patients with definite mucosal lesions and those without evidence of gut disease or with other types of gastrointestinal pathology.It is suggested that when a jejunal biopsy can readily be performed the xylose test serves little useful purpose in routine practice and can be positively misleading. It may still be useful as a screening test for referral for jejunal biopsy, provided that strict criteria of normality are applied.
在一项回顾性调查中，对152例患有各种类型胃肠道疾病的成年患者进行了D-木糖吸收试验，评估了其结果与空肠形态及最终诊断的关系。无论是单独的尿排泄率还是血清浓度，都无法充分区分有明确黏膜病变的患者与无肠道疾病证据或患有其他类型胃肠道病理的患者。有人认为，当可以轻易进行空肠活检时，木糖试验在常规实践中几乎没有什么有用的目的，而且可能会产生误导。如果应用严格的正常标准，它作为空肠活检转诊的筛查试验可能仍然有用。
