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Solid-phase synthesis of (2-isoleucine, 4-leucine) oxytocin and (2-phenylalanine, 4-leucine) oxytocin and some their pharmacological properties.

作者信息

Hruby V J, Muscio F, Gronginsky C M, Gitu P M, Saba D, Chan W Y

出版信息

J Med Chem. 1973 Jun;16(6):624-9. doi: 10.1021/jm00264a010.

DOI:10.1021/jm00264a010
PMID:4733119
Abstract
摘要

相似文献

1
Solid-phase synthesis of (2-isoleucine, 4-leucine) oxytocin and (2-phenylalanine, 4-leucine) oxytocin and some their pharmacological properties.（2-异亮氨酸，4-亮氨酸）催产素和（2-苯丙氨酸，4-亮氨酸）催产素的固相合成及其某些药理特性
J Med Chem. 1973 Jun;16(6):624-9. doi: 10.1021/jm00264a010.
2
Solid phase synthesis of (3,4-dileucine)-oxytocin and a study of some of its pharmacological properties.（3,4-二亮氨酸）-催产素的固相合成及其部分药理性质研究
J Med Chem. 1972 Jan;15(1):11-2. doi: 10.1021/jm00271a004.
3
[Synthesis and some pharmacological activities of [2-L-valine]-oxytocin and [2-L-leucine]-oxytocin.[2-L-缬氨酸]-催产素和[2-L-亮氨酸]-催产素的合成及其某些药理活性
J Med Chem. 1969 Sep;12(5):731-3. doi: 10.1021/jm00305a001.
4
The synthesis of (1-deamino,4-L-leucine)-oxytocin and (1-deamino,4-L-isoleucine)-oxytocin and some of their pharmacological properties.
J Am Chem Soc. 1970 Feb 11;92(3):677-80. doi: 10.1021/ja00706a041.
5
The synthesis and some of the pharmacological properties of [4-L-isoleucine]-oxytocin and [4-L-leucine]-oxytocin.
J Biol Chem. 1969 Jul 25;244(14):3890-4.
6
Further studies of the role of the asparagine residue in oxytocin. Synthesis and biological properties of (5- , -diaminobutyric acid)oxytocin.关于催产素中天冬酰胺残基作用的进一步研究。（5-，-二氨基丁酸）催产素的合成及生物学特性。
J Med Chem. 1972 Feb;15(2):126-8. doi: 10.1021/jm00272a002.
7
(2,4-Dileucine)exytocin. A polypeptide with natrituretic and diuretic activities, and an inhibitor of the oxytocic response of oxytocin.（2,4-二亮氨酸）催产素。一种具有利钠和利尿活性的多肽，也是催产素催产反应的抑制剂。
J Med Chem. 1971 Nov;14(11):1050-1. doi: 10.1021/jm00293a007.
8
Solid-phase syntheis and some pharmacological properties of [8-phenylalanine]-oxytocin.[8-苯丙氨酸]-催产素的固相合成及某些药理性质
Biochemistry. 1969 Sep;8(9):3592-7. doi: 10.1021/bi00837a015.
9
Synthesis of oxytocin and related diastereomers deuterated in the half-cystine positions. Comparison of solid-phase and solution methods.在半胱氨酸位置氘代的催产素及相关非对映异构体的合成。固相法与溶液法的比较。
J Org Chem. 1974 Jul 26;39(15):2207-12. doi: 10.1021/jo00929a014.
10
The synthesis and some pharmacological activities of[4-L-norvaline]-oxytocin and [4-L-norleucine]-oxytocin and their deamino analogs.
J Med Chem. 1969 Nov;12(6):1035-8. doi: 10.1021/jm00306a016.

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Detection of protein C activation in humans.人类中蛋白C活化的检测。
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Concept of internal structural controls for evaluation of inactive synthetic peptide analogs: synthesis of [Orn13,14]apamin and its guanidination to an apamin derivative with full neurotoxic activity.
用于评估无活性合成肽类似物的内部结构控制概念：[Orn13,14]蜂毒明肽的合成及其胍基化成为具有完全神经毒性活性的蜂毒明肽衍生物
Proc Natl Acad Sci U S A. 1977 Jul;74(7):2771-5. doi: 10.1073/pnas.74.7.2771.