用于检测澳大利亚抗原（乙肝表面抗原）的红细胞凝集试验的评估。
Evaluation of a red cell agglutination test for detection of Australia antigen (HG Ag).
作者信息
Germain K H, Sturdivant S K, Rightsel W A
出版信息
Appl Microbiol. 1973 Apr;25(4):524-7. doi: 10.1128/am.25.4.524-527.1973.
An investigational red cell agglutination (RCA) test was evaluated for sensitivity in detecting and titering hepatitis B antigen (HB Ag) in comparison with two counterelectrophoresis (CEP) systems and a solid-phase radioimmunoassay (RIA). The RCA procedure was found to be significantly more sensitive than the CEP methods and compares favorably in sensitivity with the solid-phase RIA, detecting even lower concentrations of the HB Ag. Since the RCA test can be completed in 2 to 3 h and requires relatively inexpensive equipment, it offers a highly sensitive and rapid procedure suitable for use in blood banks to screen donors or detect low levels of antigen in serum of patients.
对一种实验性红细胞凝集（RCA）试验进行了评估，以检测和滴定乙型肝炎抗原（HB Ag），并与两种对流免疫电泳（CEP）系统和一种固相放射免疫测定（RIA）进行比较。结果发现，RCA程序比CEP方法灵敏得多，在灵敏度方面与固相RIA相当，甚至能检测到更低浓度的HB Ag。由于RCA试验可在2至3小时内完成，且所需设备相对便宜，它提供了一种高度灵敏且快速的程序，适用于血库筛查献血者或检测患者血清中的低水平抗原。
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