一种用于测定低水平苯乙烯暴露下扁桃酸排泄量的新方法。
A new method for determination of mandelic acid excretion at low level styrene exposure.
作者信息
Slob A
出版信息
Br J Ind Med. 1973 Oct;30(4):390-3. doi: 10.1136/oem.30.4.390.
Abstract
390-393. A method is described for the determination of mandelic acid in urine. It is possible to determine styrene exposure levels in the air down to 5 mg/m. The method is based on ethyl acetate extraction of the urine, followed by a paper chromatographic combined with a gas chromatographic separation. The method was evaluated in industrial situations and compared with a method used frequently hitherto. The inclusion of a hydrolytic step indicates that part of the mandelic acid is excreted in conjugated form. Workers exposed to styrene levels in the air of less than 5 mg/m showed a very significant increase in mandelic acid excretion compared with `no exposure' conditions.
摘要
390 - 393. 描述了一种测定尿液中扁桃酸的方法。该方法能够测定空气中低至5毫克/立方米的苯乙烯暴露水平。此方法基于用乙酸乙酯萃取尿液，随后进行纸色谱结合气相色谱分离。该方法在工业环境中进行了评估，并与迄今常用的一种方法作了比较。加入水解步骤表明部分扁桃酸是以共轭形式排出的。与“无暴露”情况相比，暴露于空气中苯乙烯水平低于5毫克/立方米的工人扁桃酸排泄量显著增加。
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A rapid colorimetric method for the determination of phenylglyoxylic and mandelic acids. Its application to the urinalysis of workers exposed to styrene vapour.一种测定苯甲酰甲酸和扁桃酸的快速比色法。及其在接触苯乙烯蒸气工人尿液分析中的应用。
Br J Ind Med. 1970 Apr;27(2):150-4. doi: 10.1136/oem.27.2.150.
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