在模拟条件下接触苯乙烯的工人中扁桃酸和苯乙醛酸排泄的时间过程。
The time course of mandelic and phenylglyoxylic acid excretion in workers exposed to styrene under model conditions.
作者信息
Wilson H K, Cocker J, Purnell C J, Brown R H, Gompertz D
出版信息
Br J Ind Med. 1979 Aug;36(3):235-7. doi: 10.1136/oem.36.3.235.
Abstract
Urinary excretion of mandelic and phenylglyoxylic acids by two technicians building glass-reinforced plastic boats has been measured over a 7-day period. Peak excretion of both metabolites occurred several hours after the end of exposure. There was little relationship between urinary mandelic acid concentrations measured at the end of shift and the maximum excretion observed in samples collected after this time. It is suggested that sampling strategies devised to monitor workers exposed to styrene should reflect maximum excretion rates of urinary mandelic acid.
摘要
在7天的时间里，对两名制造玻璃钢船的技术人员尿中扁桃酸和苯乙酮酸的排泄情况进行了测定。两种代谢物的排泄峰值出现在接触结束后的数小时。轮班结束时测得的尿扁桃酸浓度与此后采集的样本中观察到的最大排泄量之间几乎没有关系。建议设计用于监测接触苯乙烯工人的采样策略应反映尿扁桃酸的最大排泄率。
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