Carnegie P R, Caspary E A, Field E J
Br J Cancer Suppl. 1973 Aug;1:219-23.
From a variety of human malignant neoplasms it is possible to prepare by acid extraction and chromatography a fraction with peak “antigenic” activity in the macrophage electrophoretic mobility (MEM) test for cancer. The activity is related to the presence of tryptophan. An analysis of the most active material so far prepared suggests important differences from myelin basic protein and from histones.
从多种人类恶性肿瘤中,通过酸提取和色谱法有可能制备出一种在癌症巨噬细胞电泳迁移率(MEM)试验中具有“抗原”活性峰值的组分。该活性与色氨酸的存在有关。对迄今为止制备的活性最强的物质进行分析表明,它与髓鞘碱性蛋白和组蛋白存在重要差异。