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乙醇在人和狗体内引发胃泌素释放。

Gastrin release by ethanol in man and in dogs.

作者信息

Becker H D, Reeder D D, Thompson J C

出版信息

Ann Surg. 1974 Jun;179(6):906-9. doi: 10.1097/00000658-197406000-00015.

Abstract

In man, oral or intravenous administration of ethanol caused a small but definite increase in peripheral serum gastrin concentration (measured by radioimmunoassay). In dogs, perfusion of the antrum with 10% ethanol caused an immediate increase in gastrin levels in the antral venous outflow. Acidification of the perfusate did not totally block the gastrin release from the antrum. Intravenous infusion of ethanol in dogs caused release of gastrin from the antrum.

摘要

在人类中,口服或静脉注射乙醇会使外周血清胃泌素浓度(通过放射免疫测定法测量)出现小幅但确定的升高。在狗身上,用10%乙醇灌注胃窦会使胃窦静脉流出液中的胃泌素水平立即升高。灌注液酸化并未完全阻断胃窦释放胃泌素。给狗静脉输注乙醇会导致胃窦释放胃泌素。

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本文引用的文献

6
Mechanism of alcoholic stimulation of gastric secretion.酒精刺激胃液分泌的机制。
Proc Soc Exp Biol Med. 1955 Jul;89(3):428-31. doi: 10.3181/00379727-89-21834.
9
Stimulation of gastric acid secretion by irrigation of the antrum with some aliphatic alcohols.
Acta Physiol Scand. 1969 Jan-Feb;75(1):1-11. doi: 10.1111/j.1748-1716.1969.tb04349.x.
10
Some factors influencing the stimulatory effect of ethanol on gastric aicd secretion during antrum application.
Acta Physiol Scand. 1969 Jan-Feb;75(1):12-27. doi: 10.1111/j.1748-1716.1969.tb04350.x.

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