Mautner V, Williams J, Sambrook J, Sharp P A, Grodzicker T
Cell. 1975 May;5(1):93-9. doi: 10.1016/0092-8674(75)90097-5.
A serological analysis has been made of the capsid antigens hexon and fiber from 17 Ad5-Ad2+ND1 recombinants that enables us to determine the phenotype of the recombinants. By correlation of this data with the genetic and physical maps of the adenovirus genome, obtained by recombination and restriction endonuclease analysis, the genes coding for the hexon and fiber have been assigned to specific locations on the adenovirus DNA.
对17种Ad5-Ad2+ND1重组体的衣壳抗原六邻体和纤维进行了血清学分析,这使我们能够确定重组体的表型。通过将这些数据与通过重组和限制性内切酶分析获得的腺病毒基因组的遗传图谱和物理图谱进行关联,编码六邻体和纤维的基因已被定位到腺病毒DNA上的特定位置。