• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Determination of chlordiazepoxide hydrochlor ide (Librium) and its major metabolites in plasma by differential pulse polarography.

作者信息

Hackman M R, Brooks M A, de Silva J A

出版信息

Anal Chem. 1974 Jul;46(8):1075-82. doi: 10.1021/ac60344a051.

DOI:10.1021/ac60344a051
PMID:4851317
Abstract
摘要

相似文献

1
Determination of chlordiazepoxide hydrochlor ide (Librium) and its major metabolites in plasma by differential pulse polarography.用微分脉冲极谱法测定血浆中氯氮䓬盐酸盐(利眠宁)及其主要代谢物。
Anal Chem. 1974 Jul;46(8):1075-82. doi: 10.1021/ac60344a051.
2
Determination of chlordiazepoxide, diazepam, and their major metabolites in blood or plasma by spectrophotodensitometry.采用分光光密度法测定血液或血浆中氯氮䓬、地西泮及其主要代谢物。
J Chromatogr. 1977 Jul 1;143(4):363-74. doi: 10.1016/s0378-4347(00)80982-2.
3
Differential pulse amperometric detection of drugs in plasma using a dropping mercury electrode as a high-performance liquid chromatographic detector.使用滴汞电极作为高效液相色谱检测器对血浆中的药物进行差分脉冲安培检测。
J Chromatogr. 1981 Feb 13;222(2):179-90. doi: 10.1016/s0378-4347(00)81051-8.
4
Cimetidine impairs elimination of chlordiazepoxide (Librium) in man.西咪替丁会损害人体中氯氮卓(利眠宁)的消除。
Ann Intern Med. 1980 Aug;93(2):266-8. doi: 10.7326/0003-4819-93-2-266.
5
Relationship between the duration of anticonvulsant activity of chlordiazepoxide and systemic levels of the parent compound and its major metabolites in mice.氯氮䓬的抗惊厥活性持续时间与母体化合物及其主要代谢产物在小鼠体内的系统水平之间的关系。
Biochem Pharmacol. 1969 Feb;18(2):303-16. doi: 10.1016/0006-2952(69)90208-1.
6
[ON THE POLAROGRAPHIC BEHAVIOR OF CHLORDIAZEPOXIDE (LIBRIUM). 2. DRUG ANALYSIS BY POLAROGRAPHY OR OSCILLOPOLAROGRAPHY].
Arch Pharm Ber Dtsch Pharm Ges. 1963 Jun;296:396-403. doi: 10.1002/ardp.19632960608.
7
Polarographic determination of chlordiazepoxide and diazepan in toxicological analyses.极谱法在毒理学分析中测定氯氮卓和地西泮
J Forensic Sci. 1965 Jul;10(3):282-93.
8
Pharmacokinetic model for chlordiazepoxide--HCl in the dog.狗体内氯氮䓬盐酸盐的药代动力学模型。
J Pharm Sci. 1970 Nov;59(11):1569-74. doi: 10.1002/jps.2600591105.
9
Determination of chlordiazepoxide plasma concentrations by electron capture gas-liquid chromatography.用电子捕获气液色谱法测定氯氮卓的血浆浓度。
J Chromatogr. 1971 Oct;61(2):237-52. doi: 10.1016/s0021-9673(00)92416-6.
10
Quantitation of chlordiazepoxide and its metabolites in biological fluids by thin-layer chromatography.
J Chromatogr. 1978 Nov 1;146(3):473-80. doi: 10.1016/s0378-4347(00)81206-2.

引用本文的文献

1
Review of Electroanalytical-Based Approaches for the Determination of Benzodiazepines.基于电分析方法的苯二氮䓬类药物测定综述。
Biosensors (Basel). 2019 Nov 2;9(4):130. doi: 10.3390/bios9040130.
2
Pharmacologically active drug metabolites: therapeutic and toxic activities, plasma and urine data in man, accumulation in renal failure.药理活性药物代谢物:治疗及毒性活性、人体血浆及尿液数据、肾衰竭时的蓄积情况
Clin Pharmacokinet. 1976 Nov-Dec;1(6):426-43. doi: 10.2165/00003088-197601060-00003.
3
Clinical pharmacokinetics of chlordiazepoxide.
氯氮䓬的临床药代动力学
Clin Pharmacokinet. 1978 Sep-Oct;3(5):381-94. doi: 10.2165/00003088-197803050-00004.