Favaro S, Ossi E, Marati A, Faggion T, Baggio B, Inecco A, Antonello A, Borsatti A
Ann Sclavo. 1979 Mar-Apr;21(2):229-34.
The effect of up to 6months antibacterial treatment on both urine culture and the presence of antibody-coated bacteria in the urinary sediment was examined in 15 patients with upper urinary-tract infection. At the end of the sixth month all the patients had sterile urine, while about one half still demonstrated antibody-coated bacteria in their sediment. Such a finding strongly suggests that urine culture is "per se" insufficient to exclude the presence of bacteria in the renal parenchyma, and that the evaluation of antibody-coated bacteria might be a better way to watch the effect of treatment in upper urinary-tract infections.
对15例上尿路感染患者进行了为期6个月的抗菌治疗,观察其对尿培养及尿沉渣中抗体包被细菌的影响。在第六个月末,所有患者的尿液均无菌,但约一半患者的尿沉渣中仍显示有抗体包被细菌。这一发现有力地表明,尿培养“本身”不足以排除肾实质中细菌的存在,而评估抗体包被细菌可能是观察上尿路感染治疗效果的更好方法。