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相似文献

1
Physiological role of 70S ribosomes in bacteria.70S核糖体在细菌中的生理作用。
Proc Natl Acad Sci U S A. 1969 Feb;62(2):574-80. doi: 10.1073/pnas.62.2.574.
2
Stabilization and breakdown of Escherichia coli messenger ribonucleic acid in the presence of chloramphenicol.氯霉素存在时大肠杆菌信使核糖核酸的稳定性与降解
Biochemistry. 1972 Aug 1;11(16):3054-9. doi: 10.1021/bi00766a017.
3
Nucleic acid and ribosome synthesis by Escherichia coli incubated in 5',5',5'-trifluoroleucine.在5',5',5'-三氟亮氨酸中培养的大肠杆菌的核酸和核糖体合成
Biochim Biophys Acta. 1971 Feb 11;228(3):701-18. doi: 10.1016/0005-2787(71)90735-0.
4
Accumulation of 70S monoribosomes in Escherichia coli after energy source shift-down.能量源下调后大肠杆菌中70S单核糖体的积累。
J Bacteriol. 1972 Jul;111(1):142-51. doi: 10.1128/jb.111.1.142-151.1972.
5
Reutilization of ribosomal proteins in vivo for the formation of new ribosomal particles in Escherichia coli B.核糖体蛋白在体内的再利用以形成大肠杆菌B中的新核糖体颗粒
Biochim Biophys Acta. 1969 Feb 18;174(2):566-73. doi: 10.1016/0005-2787(69)90286-x.
6
Polysome stability in relaxed and stringent strain of Escherichia coli during amino acid starvation.氨基酸饥饿期间大肠杆菌松弛型和严谨型菌株中的多核糖体稳定性。
J Bacteriol. 1970 Jun;102(3):666-71. doi: 10.1128/jb.102.3.666-671.1970.
7
[Formation of ribosomes in Escherichia coli deficient in phosphate].
Bull Soc Chim Biol (Paris). 1967;49(3):233-45.
8
Regulation of macromolecular synthesis by putrescine in a conditional Escherichia coli putrescine auxotroph.腐胺对条件性大肠杆菌腐胺营养缺陷型中大分子合成的调控
J Bacteriol. 1972 Oct;112(1):30-9. doi: 10.1128/jb.112.1.30-39.1972.
9
Altered ribosomes after inhibition of Escherichia coli by rifampicin.利福平抑制大肠杆菌后核糖体的改变。
Biochem J. 1971 Feb;121(3):391-8. doi: 10.1042/bj1210391.
10
Ribosomal protein pool of Escherichia coli.大肠杆菌的核糖体蛋白库
Biochim Biophys Acta. 1970 Aug 8;213(2):451-68. doi: 10.1016/0005-2787(70)90052-3.

引用本文的文献

1
Requirement for extraction of polyribosomes from barley tissue.从大麦组织中提取多核糖体的要求。
Plant Physiol. 1972 May;49(5):733-9. doi: 10.1104/pp.49.5.733.
2
Bacterial ribosome.细菌核糖体
Bacteriol Rev. 1970 Sep;34(3):228-77. doi: 10.1128/br.34.3.228-277.1970.
3
Mechanism of protein synthesis inhibition during stationary phase in Bacillus stearothermophilus.嗜热脂肪芽孢杆菌稳定期蛋白质合成抑制机制。
Mol Cell Biochem. 1980 Jun 18;31(2):97-103. doi: 10.1007/BF00240815.
4
Control of single ribosome formation by an initiation factor for protein synthesis.通过蛋白质合成起始因子对单个核糖体形成的控制。
Proc Natl Acad Sci U S A. 1971 Oct;68(10):2458-62. doi: 10.1073/pnas.68.10.2458.
5
Polyribosomes of Escherichia coli. II. In vivo and in vitro studies on DNA bound and cytoplasmic polysomes.
Mol Gen Genet. 1971;112(3):208-20. doi: 10.1007/BF00269173.
6
Association factor of ribosomal subunits from Bacillus stearothermophilus.嗜热脂肪芽孢杆菌核糖体亚基的缔合因子
Proc Natl Acad Sci U S A. 1971 Nov;68(11):2822-5. doi: 10.1073/pnas.68.11.2822.
7
Characterization of a nonsense mutation affecting the acitivity of the dissociation factor of Escherichia coli ribosomes.
Mol Gen Genet. 1971;110(3):211-7. doi: 10.1007/BF00337834.
8
Dissociation of 70S ribosomes: some properties of the dissociating factor from Bacillus stearothermophilus and Escherichia coli.70S核糖体的解离：嗜热脂肪芽孢杆菌和大肠杆菌解离因子的一些特性
Proc Natl Acad Sci U S A. 1969 Oct;64(2):654-60. doi: 10.1073/pnas.64.2.654.
9
Mechanism of protein biosynthesis.蛋白质生物合成机制。
Bacteriol Rev. 1969 Jun;33(2):264-301. doi: 10.1128/br.33.2.264-301.1969.
10
Localization of the stringent protein of Escherichia coli on the 50S ribosomal subunit.大肠杆菌严谨反应蛋白在50S核糖体亚基上的定位
Proc Natl Acad Sci U S A. 1974 Mar;71(3):820-4. doi: 10.1073/pnas.71.3.820.

本文引用的文献

1
PHAGE f2 RNA-DIRECTED BINDING OF FORMYLMETHIONYL-TRNA TO RIBOSOMES AND THE ROLE OF 30S RIBOSOMAL SUBUNITS IN INITIATION OF PROTEIN SYNTHESIS.噬菌体f2的甲酰甲硫氨酰 - tRNA与核糖体的RNA指导结合以及30S核糖体亚基在蛋白质合成起始中的作用。
Proc Natl Acad Sci U S A. 1967 Sep;58(3):946-53. doi: 10.1073/pnas.58.3.946.
2
AN ESTIMATE OF THE SIZE OF THE RIBOSOMAL SITE FOR MESSENGER RNA BINDING.信使核糖核酸结合的核糖体位点大小的估计
Proc Natl Acad Sci U S A. 1964 May;51(5):834-9. doi: 10.1073/pnas.51.5.834.
3
Studies on the genesis of polyribosomes. I. Origin and significance of the subribosomal particles.多核糖体起源的研究。I. 核糖体亚基颗粒的起源及意义。
J Mol Biol. 1965 Sep;13(2):496-510. doi: 10.1016/s0022-2836(65)80112-7.
4
Protein synthesis and ribosomal distribution at different growth stages in Bacillus stearothermophilus.
Biochim Biophys Acta. 1968 Oct 29;166(3):760-2. doi: 10.1016/0005-2787(68)90397-3.
5
Polyribosomes in Azotobacter vinelandii. I. Isolation, characterization and distribution of ribosomes, polyribosomes and subunits in logarithmically growing azotobacter.棕色固氮菌中的多核糖体。I. 对数生长期棕色固氮菌中核糖体、多核糖体和亚基的分离、表征及分布
Biochim Biophys Acta. 1968 Jul 23;161(2):386-401.
6
The replication of bacteriophage MS2. VI. Interaction between bacteriophage RNA and cellular components in MS2-infected Escherichia coli.噬菌体MS2的复制。VI. 噬菌体MS2感染的大肠杆菌中噬菌体RNA与细胞成分之间的相互作用。
J Mol Biol. 1967 Feb 14;23(3):495-521. doi: 10.1016/s0022-2836(67)80121-9.
7
Polyribosome metabolism in Escherichia coli. I. Extraction of polyribosomes and ribosomal subunits from fragile, growing Escherichia coli.大肠杆菌中的多核糖体代谢。I. 从脆弱的、生长中的大肠杆菌中提取多核糖体和核糖体亚基。
J Mol Biol. 1966 Sep;20(1):123-43. doi: 10.1016/0022-2836(66)90122-7.
8
Polyribosomes of Escherichia coli. Re-formation during recovery from glucose starvation.大肠杆菌的多核糖体。从葡萄糖饥饿恢复过程中的重新形成。
J Biol Chem. 1967 Mar 10;242(5):1069-73.
9
Polyribosomes of Escherichia coli. Breakdown during glucose starvation.大肠杆菌的多核糖体。葡萄糖饥饿期间的分解
J Biol Chem. 1967 Mar 10;242(5):1065-8.
10
Polysomes extracted from Escherichia coli by freeze-thaw-lysozyme lysis.通过冻融-溶菌酶裂解从大肠杆菌中提取的多核糖体。
Science. 1966 Sep 2;153(3740):1119-20. doi: 10.1126/science.153.3740.1119.

70S核糖体在细菌中的生理作用。

Physiological role of 70S ribosomes in bacteria.

作者信息

Algranati I D, Gonzalez N S, Bade E G

出版信息

Proc Natl Acad Sci U S A. 1969 Feb;62(2):574-80. doi: 10.1073/pnas.62.2.574.

DOI:10.1073/pnas.62.2.574
PMID:4894332
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC277844/
Abstract

Evidence is presented indicating that free 70S ribosomes are real components of Bacillus stearothermophilus and Escherichia coli in exponential and stationary phases of growth. After pulses of radioactive leucine or uracil were given, protein synthesis was instantaneously stopped by chloramphenicol, or polypeptide growth was allowed to proceed to completion in slowly cooled cells. Analysis of label distribution in sucrose gradients showed that 70S monomers, and not subunits, are final products of translation.A ribosome cycle for protein synthesis in bacteria is proposed.

摘要

有证据表明，在嗜热脂肪芽孢杆菌和大肠杆菌生长的指数期和稳定期，游离70S核糖体是其真实的组成部分。在给予放射性亮氨酸或尿嘧啶脉冲后，氯霉素可使蛋白质合成瞬间停止，或者在缓慢冷却的细胞中让多肽生长进行至完成。对蔗糖梯度中标记分布的分析表明，翻译的最终产物是70S单体，而非亚基。本文提出了细菌蛋白质合成的核糖体循环。