Pereira M S, Blake J M, Macrae A D
Br Med J. 1969 Nov 29;4(5682):526-7. doi: 10.1136/bmj.4.5682.526.
In relation to the study of infectious mononucleosis a survey of the prevalence of antibody to EB virus was made on the sera of persons of varying age from several different areas in England by the indirect immunofluorescence technique. About half those tested were found to have acquired antibody by the age of 4 years and there was a further significant increase in the proportion of those positive between the ages of 15 and 24 years. The finding of seroconversion in two patients who developed infectious mononucleosis provides further support for an association between EB virus and this condition.
关于传染性单核细胞增多症的研究,通过间接免疫荧光技术对来自英格兰不同地区的不同年龄段人群的血清进行了EB病毒抗体患病率调查。约一半的受测者在4岁时已获得抗体,且在15至24岁之间抗体呈阳性的比例进一步显著增加。两名患传染性单核细胞增多症的患者出现血清转化的这一发现,为EB病毒与该病之间的关联提供了进一步的支持。