Edwards J M, McSwiggan D A
J Clin Pathol. 1974 Aug;27(8):647-51. doi: 10.1136/jcp.27.8.647.
A modification of the test for EB virus/IgM introduced by Schmitz and Scherer (1972) is described. It is simple and gives reproducible results.EB virus/IgM was demonstrated in all but one case of infectious mononucleosis and in students with minor illness shown to have acquired EB virus/IgG recently. Unlike the EB virus/IgG, the IgM disappears within a few months. Although the Paul-Bunnell-Davidsohn test is still the test of choice for the diagnosis of infectious mononucleosis, the EB virus/IgM test could be useful to establish a diagnosis of current or recent EB virus infection where the Paul-Bunnell-Davidsohn test was negative or equivocal.
本文描述了对施密茨和舍勒(1972年)提出的EB病毒/IgM检测方法的一种改进。该方法简单且结果可重复。在除1例传染性单核细胞增多症外的所有病例以及近期感染过EB病毒/IgG的轻症学生中均检测到了EB病毒/IgM。与EB病毒/IgG不同,IgM在几个月内就会消失。尽管保罗 - 邦内尔 - 戴维森试验仍是诊断传染性单核细胞增多症的首选检测方法,但在保罗 - 邦内尔 - 戴维森试验为阴性或结果不明确的情况下,EB病毒/IgM检测对于确诊当前或近期的EB病毒感染可能会有帮助。