大肠杆菌的转酮醇酶突变体
Transketolase mutants of Escherichia coli.
作者信息
Josephson B L, Fraenkel D G
出版信息
J Bacteriol. 1969 Dec;100(3):1289-95. doi: 10.1128/jb.100.3.1289-1295.1969.
Abstract
Transketolase mutants have been selected after ethyl methane sulfonate mutagenesis of Escherichia coli. These strains are unable to grow on any pentose and, in addition, require a supplement of aromatic amino acids or shikimic acid for normal growth on any other carbon source. Revertants are normal in both respects and also contain transketolase. Transketolase mutants do not require exogenous pentose for growth. Preliminary genetic mapping of the locus is presented.
摘要
通过对大肠杆菌进行甲磺酸乙酯诱变后筛选出了转酮醇酶突变体。这些菌株无法在任何戊糖上生长，此外，在任何其他碳源上正常生长都需要补充芳香族氨基酸或莽草酸。回复突变体在这两个方面都是正常的，并且也含有转酮醇酶。转酮醇酶突变体生长不需要外源戊糖。本文给出了该基因座的初步遗传图谱。
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