鼠伤寒沙门氏菌组氨酸操纵子中的转录起始
Transcription initiation in the histidine operon of Salmonella typhimurium.
作者信息
Atkins J F, Loper J C
出版信息
Proc Natl Acad Sci U S A. 1970 Apr;65(4):925-32. doi: 10.1073/pnas.65.4.925.
Abstract
Evidence is presented for two natural transcription initiators positioned internally in the histidine operon of Salmonella typhimurium. They were detected using highly polar S. typhimurium his mutants as recipients for F' Escherichia coli his episomes. These intergeneric complementation tests provide a sensitive method for the detection of other initiators and of terminators. That at least part of the operator for the his operon lies distal to the transcription initiator is suggested by transduction analysis of a new highly polar mutant described in this paper.
摘要
有证据表明，在鼠伤寒沙门氏菌的组氨酸操纵子内部存在两个天然转录起始位点。利用极性很强的鼠伤寒沙门氏菌his突变体作为F'大肠杆菌his附加体的受体来检测它们。这些属间互补试验为检测其他起始位点和终止位点提供了一种灵敏的方法。本文描述的一个新的极性很强的突变体的转导分析表明，组氨酸操纵子的操纵基因至少有一部分位于转录起始位点的远端。
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本文引用的文献
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Fine structure mapping by complete transduction between histidine-requiring Salmonella mutants.通过在组氨酸需求型沙门氏菌突变体之间进行完全转导进行精细结构作图。
J Gen Microbiol. 1960 Apr;22:323-53. doi: 10.1099/00221287-22-2-323.
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Complementation mapping by abortive transduction of histidine requiring Salmonella mutants.利用组氨酸缺陷型沙门氏菌突变体的流产转导进行互补作图。
J Gen Microbiol. 1960 Apr;22:354-68. doi: 10.1099/00221287-22-2-354.
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Hybrids of Escherichia and Salmonella.大肠杆菌与沙门氏菌的杂交体。
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The genetic control of the enzymes of histidine biosynthesis in Salmonella typhimurium.鼠伤寒沙门氏菌中组氨酸生物合成酶的遗传控制
J Gen Microbiol. 1960 Apr;22:369-78. doi: 10.1099/00221287-22-2-369.
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A phage P22 gene controlling integration of prophage.一个控制原噬菌体整合的噬菌体P22基因。
Virology. 1967 Feb;31(2):207-16. doi: 10.1016/0042-6822(67)90164-x.
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Chain initiation in a polycistronic message: sequential versus simultaneous derepression of the enzymes for histidine biosynthesis in Salmonella typhimurium.多顺反子信息中的链起始：鼠伤寒沙门氏菌中组氨酸生物合成酶的顺序去阻遏与同时去阻遏
Proc Natl Acad Sci U S A. 1967 Jun;57(6):1857-64. doi: 10.1073/pnas.57.6.1857.
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Histidine regulatory mutants in Salmonella typhimurium. I. Isolation and general properties.鼠伤寒沙门氏菌中的组氨酸调节突变体。I. 分离与一般特性。
J Mol Biol. 1966 Dec 28;22(2):305-23. doi: 10.1016/0022-2836(66)90134-3.
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Isolation of the fourth (isomerase) of histidine biosynthesis from Salmonella typhimurium.从鼠伤寒沙门氏菌中分离组氨酸生物合成的第四种（异构酶）。
J Biol Chem. 1966 Jul 25;241(14):3262-9.
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A transcription-initiating mutation within a structural gene of the tryptophan operon.色氨酸操纵子结构基因内的转录起始突变。
J Mol Biol. 1969 May 14;41(3):317-28. doi: 10.1016/0022-2836(69)90278-2.
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