Shkhvatsabaia I K, Patrusheva I F, Nekrasova A A
Kardiologiia. 1979 Aug;19(8):31-6.
Examination was conducted of 33 healthy persons and 85 individuals suffering from hypertensive disease (stage IB, 52 patients and stage IIB, 33 patients) from 18 to 45 years of age. The basal level of three steroid hormones (progesterone, aldosterone, hydrocortisone) was studied by the radio-immune method. It was established that stabilization of arterial pressure is attended by an increase in the aldosterone/progresterone and aldosterone/hydrocortisone ratios. During one stage of the disease the basal level of steroid hormones varied within different limits, particularly in labile hypertension. The interconnection of blood plasma steroid hormone level and the age, duration of the disease, aggravation by hereditary factors, level of arterial pressure and daily and basal natriuresis was revealed.
对33名健康人和85名年龄在18至45岁之间患有高血压疾病（1B期52例患者和IIB期33例患者）的个体进行了检查。采用放射免疫法研究了三种类固醇激素（孕酮、醛固酮、氢化可的松）的基础水平。结果表明，动脉压稳定伴随着醛固酮/孕酮和醛固酮/氢化可的松比值的升高。在疾病的一个阶段，类固醇激素的基础水平在不同范围内变化，特别是在不稳定型高血压中。揭示了血浆类固醇激素水平与年龄、病程、遗传因素加重情况、动脉压水平以及每日和基础钠尿之间的相互关系。
