Minkus R, Moffet H L
Appl Microbiol. 1971 Nov;22(5):805-8. doi: 10.1128/am.22.5.805-808.1971.
A prospective study was made of 1,000 consecutive duplicate blood cultures obtained from sick children to evaluate the usefulness of sodium polyanethol sulfonate (SPS). With the small volumes of blood (1 to 5 ml) usually obtained for blood cultures in children, SPS did not increase the frequency of recovery of organisms judged to be associated with clinical infections, with the possible exception of Diplococcus pneumoniae. However, the use of SPS was associated with an increased frequency of recovery of organisms judged to be contaminants, such as Staphylococcus epidermidis and propionibacteria, possibly because SPS enhanced the recovery of a very small inoculum of skin bacteria.
对从患病儿童中连续采集的1000份重复血培养样本进行了一项前瞻性研究,以评估聚茴香脑磺酸钠(SPS)的效用。由于儿童血培养通常采集的血量较少(1至5毫升),SPS并没有增加被判定与临床感染相关的微生物的检出频率,肺炎双球菌可能除外。然而,使用SPS与被判定为污染物的微生物(如表皮葡萄球菌和丙酸杆菌)的检出频率增加有关,这可能是因为SPS提高了极少量皮肤细菌接种物的检出率。