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弹状病毒科。病毒分类国际委员会弹状病毒研究小组报告。

Rhabdoviridae. Report of the Rhabdovirus Study Group, International Committee on Taxonomy of Viruses.

作者信息

Brown F, Bishop D H, Crick J, Francki R I, Holland J J, Hull R, Johnson K, Martelli G, Murphy F A, Obijeski J F, Peters D, Pringle C R, Reichmann M E, Schneider L G, Shope R E, Simpson D I, Summers D F, Wagner R R

出版信息

Intervirology. 1979;12(1):1-7. doi: 10.1159/000149062.

Abstract

The family Rhabdoviridae comprises approximately 75 viruses infecting vertebrates, invertebrates and plants. The main characteristics of the member viruses are: (i) the viruses infecting vertebrates and invertebrates are bullet-shaped and the viruses infecting plants are usually bacilliform; (ii) the viruses have particle lengths varying from 130 to 380 nm and widths varying from 60 to 95 nm; (iii) the viruses possess unit-membrane envelopes from which protrude spikes 5 to 10 nm long; (iv) the viruses have precisely coiled helical nuecleocapsids with a diameter of approx. 50 nm; (v) most of the viruses which have been studied contain 5 proteins; the prototype, vesicular stomatitis virus, contains proteins designated L (large), G (glycoprotein), N (nucleoprotein), NS (nonstructural) and M (matrix); N or NS is phosphorylated in most members which have been studied; (vi) the viruses contain single-stranded RNA which is transcribed into several messenger RNA species with sizes corresponding to the structural proteins; (vii) the nucleocapsid contains the RNA-dependent RNA polymerase and is infectious; and (viii) many of the viruses produce morphologically distinct defective-interfering (T) particles.

摘要

弹状病毒科包含约75种感染脊椎动物、无脊椎动物和植物的病毒。该科成员病毒的主要特征如下:(i)感染脊椎动物和无脊椎动物的病毒呈子弹状,而感染植物的病毒通常呈杆状;(ii)病毒粒子长度在130至380纳米之间,宽度在60至95纳米之间;(iii)病毒具有单位膜包膜,包膜上伸出5至10纳米长的刺突;(iv)病毒具有精确盘绕的螺旋核衣壳,直径约为50纳米;(v)大多数已研究的病毒含有5种蛋白质;原型病毒水疱性口炎病毒含有名为L(大)、G(糖蛋白)、N(核蛋白)、NS(非结构)和M(基质)的蛋白质;在大多数已研究的成员中,N或NS会发生磷酸化;(vi)病毒含有单链RNA,该RNA被转录成几种信使RNA,其大小与结构蛋白相对应;(vii)核衣壳含有RNA依赖性RNA聚合酶且具有感染性;(viii)许多病毒会产生形态上不同的缺陷干扰(T)颗粒。

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