Wilson E R, Takei Y, Bikoff W T, O'Brien M S, Tindall G T, Boehm W M
Neurosurgery. 1979 Sep;5(3):356-64.
Three cases of rare primary intracranial yolk sac tumor are reported. Two cases had a pineal location, whereas the third presented as a suprasellar mass. After the placement of ventriculoperitoneal shunts for relief of hydrocephalus, all of the patients developed metastases restricted to the peritoneum, as demonstrated by autopsy in one patient (Case 1) and clinical and radiographic evidence in two patients (Cases 2 and 3). The peritoneal metastases were directly associated with the death of one patient, but were successfully treated with chemotherapy in another patient, who is still alive more than 2.5 years after initial presentation. The value of ascitic fluid cytology and alpha-fetoprotein determination in the diagnosis of this complication was demonstrated in one patient. These cases emphasize the need for awareness of this mode of metastasis and its potentially lethal effect.
报告了3例罕见的原发性颅内卵黄囊瘤。2例位于松果体区，而第3例表现为鞍上肿块。在放置脑室腹腔分流术以缓解脑积水后，所有患者均发生了局限于腹膜的转移，其中1例患者（病例1）经尸检证实，2例患者（病例2和病例3）有临床和影像学证据。腹膜转移直接导致1例患者死亡，但另1例患者通过化疗成功治疗，自初次就诊后已存活超过2.5年。1例患者证实了腹水细胞学检查和甲胎蛋白测定在诊断该并发症中的价值。这些病例强调了需要认识到这种转移方式及其潜在的致命影响。
