随机单核细胞迁移：与迟发型超敏皮肤反应的体外相关性
Random monocyte migration: an in vitro correlation with the delayed hypersensitivity skin reaction.
作者信息
Hawes C S, Kemp A S, Jones W R
出版信息
Clin Exp Immunol. 1979 Sep;37(3):567-71.
The in vitro random migration and chemotactic activity of peripheral blood monocytes and neutrophils was compared with the delayed hypersensitivity skin test to streptokinase-streptodornase in fourteen normal subjects. A significant positive correlation (P less than 0.001) was observed between the random migration of monocytes and the size of the skin test reaction. No significant correlation was found with random neutrophil migration or monocyte and neutrophil chemotactic responses. These results indicate that the in vitro random mobility of monocytes is related to the in vivo expression of a delayed-type hypersensitivity skin reaction.
在14名正常受试者中，将外周血单核细胞和中性粒细胞的体外随机迁移及趋化活性与链激酶-链道酶的迟发型超敏皮肤试验进行了比较。观察到单核细胞的随机迁移与皮肤试验反应的大小之间存在显著正相关（P小于0.001）。未发现与中性粒细胞随机迁移或单核细胞及中性粒细胞趋化反应有显著相关性。这些结果表明，单核细胞的体外随机迁移能力与迟发型超敏皮肤反应的体内表达有关。
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