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The intravenous toxicity and clearance of bupivacaine in man.

作者信息

Mather L E, Long G J, Thomas J

出版信息

Clin Pharmacol Ther. 1971 Nov-Dec;12(6):935-43. doi: 10.1002/cpt1971126935.

DOI:10.1002/cpt1971126935
PMID:5134997
Abstract
摘要

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1
The intravenous toxicity and clearance of bupivacaine in man.布比卡因在人体中的静脉毒性及清除率
Clin Pharmacol Ther. 1971 Nov-Dec;12(6):935-43. doi: 10.1002/cpt1971126935.
2
Pharmacokinetic study of the local anaesthetics bupivacaine (Marcain) and etidocaine (Duranest) in man.局部麻醉药布比卡因（耐乐品）和依替卡因（利多卡因）在人体中的药代动力学研究。
Br J Anaesth. 1973 Oct;45(10):1010-2. doi: 10.1093/bja/45.10.1010.
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[Decomposition kinetics of bupivacaine in biological specimens].[布比卡因在生物样本中的分解动力学]
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Electrocardiographic and hemodynamic effects of intravenous infusion of bupivacaine, ropivacaine, levobupivacaine, and lidocaine in anesthetized ewes.布比卡因、罗哌卡因、左旋布比卡因和利多卡因静脉输注对麻醉母羊的心电图和血流动力学影响。
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6
Rapid and specific precolumn extraction high-performance liquid chromatographic assay for bupivacaine in human serum.
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Continuous infusion of 0.5% bupivacaine for local analgesia: what are "toxic" blood levels?持续输注0.5%布比卡因用于局部镇痛：“中毒”血药浓度是多少？
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Lipid resuscitation: listening to our patients and learning from our models.
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Influence of bupivacaine injection dose rate on cardiovascular depression, subsequent hemodynamic course, and related bupivacaine plasma levels in piglets.布比卡因注射速率对幼猪心血管抑制、随后的血液动力学过程及相关布比卡因血浆水平的影响。
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Determination of bupivacaine and metabolites in rat urine using capillary electrophoresis with mass spectrometric detection.采用毛细管电泳-质谱检测法测定大鼠尿液中的布比卡因及其代谢物。
Electrophoresis. 2003 Jul;24(14):2340-7. doi: 10.1002/elps.200305469.
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Cardiotoxicity with modern local anaesthetics: is there a safer choice?现代局部麻醉药的心脏毒性：是否存在更安全的选择？
Drugs. 2001;61(3):333-42. doi: 10.2165/00003495-200161030-00002.
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Determination of bupivacaine and three of its metabolites in rat urine by capillary electrophoresis.毛细管电泳法测定大鼠尿液中布比卡因及其三种代谢物
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Vasoactive actions of local anaesthetics on human isolated umbilical veins and arteries.局部麻醉药对人离体脐静脉和动脉的血管活性作用。
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Critical compilation of terminal half-lives, percent excreted unchanged, and changes of half-life in renal and hepatic dysfunction for studies in humans with references.对人类研究中终末半衰期、原形药物排泄百分比以及肾功能和肝功能不全时半衰期变化进行批判性汇编，并列出参考文献。
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Clinical pharmacokinetics of local anaesthetics.局部麻醉药的临床药代动力学
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