Costello J F, Sudlow M F, Douglas N J, Flenley D C
Lancet. 1975 Oct 11;2(7937):678-81. doi: 10.1016/s0140-6736(75)90776-x.
The acute effects on airway function of smoking one cigarette of a tobacco substitute 'New Smoking Material' (NSM), one cigarette of conventional tobacco, and one cigarette containing 70% tobacco and 30% NSM, were studied in 6 healthy nonsmokers and 6 healthy smokers. None of the cigarettes produced any change in three tests of small-airway function (flow-volume curves, closing volume, frequency dependence of compliance). However, smoking either one conventional tobacco cigarette or the 30% NSM/70% tobacco cigarette produced an acute fall in specific airways conductance, of similar degree with both cigarettes, whereas the 100% NSM cigarette produced no such change.
在6名健康非吸烟者和6名健康吸烟者中，研究了吸一支烟草替代品“新吸烟材料”（NSM）香烟、一支传统烟草香烟以及一支含有70%烟草和30%NSM的香烟对气道功能的急性影响。在三项小气道功能测试（流量-容积曲线、闭合容积、顺应性频率依赖性）中，这些香烟均未产生任何变化。然而，吸一支传统烟草香烟或30%NSM/70%烟草香烟都会导致比气道传导率急性下降，两种香烟下降程度相似，而100%NSM香烟则未产生此类变化。
