慢性乙型肝炎病毒感染中单核细胞干扰素产生与病毒复制之间缺乏相关性。
Lack of correlation between interferon production of mononuclear cells and virus replication in chronic hepatitis B virus infection.
作者信息
Kinoshita R, Miura K, Suzuki S, Uchino H
出版信息
J Clin Microbiol. 1979 Dec;10(6):923-5. doi: 10.1128/jcm.10.6.923-925.1979.
Abstract
Interferon production in hepatitis B virus carriers with normal liver functions was preserved, whereas in carriers with chronic hepatitis it was depressed. The lower interferon production in hepatitis B virus carriers with chronic hepatitis appears to be the result rather than the cause of chronic hepatic disease.
摘要
肝功能正常的乙肝病毒携带者的干扰素产生功能得以保留，而慢性肝炎携带者的干扰素产生功能则受到抑制。慢性肝炎乙肝病毒携带者中较低的干扰素产生功能似乎是慢性肝病的结果而非病因。
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Lack of correlation between interferon production of mononuclear cells and virus replication in chronic hepatitis B virus infection.慢性乙型肝炎病毒感染中单核细胞干扰素产生与病毒复制之间缺乏相关性。
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本文引用的文献
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DNA polymerase associated with human hepatitis B antigen.与人类乙肝抗原相关的DNA聚合酶
J Virol. 1973 Nov;12(5):995-1005. doi: 10.1128/JVI.12.5.995-1005.1973.
2
Effect of human leukocyte interferon on hepatitis B virus infection in patients with chronic active hepatitis.人白细胞干扰素对慢性活动性肝炎患者乙型肝炎病毒感染的影响。
N Engl J Med. 1976 Sep 2;295(10):517-22. doi: 10.1056/NEJM197609022951001.
3
Role of interferon in the pathogenesis of viral diseases of mice as demonstrated by the use of anti-interferon serum. V. Protective role in mouse hepatitis virus type 3 infection of susceptible and resistant strains of mice.通过使用抗干扰素血清所证明的干扰素在小鼠病毒性疾病发病机制中的作用。V. 在3型小鼠肝炎病毒感染易感和抗性小鼠品系中的保护作用。
J Immunol. 1978 May;120(5):1616-9.
4
The use of interferon in viral hepatitis B.干扰素在乙型病毒性肝炎中的应用。
Tex Rep Biol Med. 1977;35:516-22.
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Decreased interferon response by lymphocytes from children with chronic hepatitis.慢性肝炎患儿淋巴细胞的干扰素反应降低。
J Infect Dis. 1975 Oct;132(4):459-61. doi: 10.1093/infdis/132.4.459.
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Studies on an inhibitory factor to phytohemagglutinin-induced lymphocyte transformation found in the serum of patients with various liver diseases.对各种肝病患者血清中发现的一种抑制植物血凝素诱导淋巴细胞转化的因子的研究。
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