参与免疫反应的细胞。13. 与抗体形成和免疫耐受相关的细胞相互作用的本质：一个统一的假说。
Cells involved in the immune response. 13. The nature of the cellular interactions relating antibody formation and immunologic tolerance: a unified hypothesis.
作者信息
Richter M
出版信息
Proc Natl Acad Sci U S A. 1969 Sep;64(1):75-80. doi: 10.1073/pnas.64.1.75.
Abstract
The various cells and cell pathways involved in the induction of the primary humoral immune response have been discussed from the point of view of the unitary, as opposed to the multiple, pathway concept. The immunocompetent cells made unresponsive in the immunologically tolerant animal and the cells capable of responding with antibody formation were considered. It is concluded that there exist multiple cellular pathways through which the humoral immune response may be expressed.
摘要
从单一途径而非多途径概念的角度，讨论了参与初次体液免疫应答诱导的各种细胞和细胞途径。研究了在免疫耐受动物中变得无反应的免疫活性细胞以及能够产生抗体形成反应的细胞。得出的结论是，存在多种细胞途径，通过这些途径可以表达体液免疫应答。
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本文引用的文献
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A THREE-CELL INTERACTION REQUIRED FOR THE INDUCTION OF THE PRIMARY IMMUNE RESPONSE in vitro.体外诱导初次免疫反应所需的三细胞相互作用。
Proc Natl Acad Sci U S A. 1968 Oct;61(2):542-7. doi: 10.1073/pnas.61.2.542.
2
THE MECHANISM OF TOLERANCE PRODUCED IN RATS TO SHEEP ERYTHROCYTES. I. PLAQUE-FORMING CELL AND ANTIBODY RESPONSE TO SINGLE AND MULTIPLE INJECTIONS OF ANTIGEN.大鼠对绵羊红细胞产生耐受性的机制。I. 对单次和多次注射抗原的噬斑形成细胞及抗体反应。
J Exp Med. 1965 May 1;121(5):671-81. doi: 10.1084/jem.121.5.671.
3
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Role of macrophages in antibody production. Immune response to sheep red blood cells.巨噬细胞在抗体产生中的作用。对绵羊红细胞的免疫反应。
J Immunol. 1967 Oct;99(4):744-50.
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The role of macrophages in the induction of antibody in x-irradiated animals.巨噬细胞在受X射线照射动物体内抗体诱导中的作用。
Immunology. 1967 Feb;12(2):197-206.
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Macrophages from tolerant rabbits as mediators of a specific immunological response in vitro.来自耐受兔的巨噬细胞作为体外特异性免疫反应的介质。
Immunology. 1967 Feb;12(2):159-63.
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The coexistence of antibody with antigen during immunological paralysis to BSA.在对牛血清白蛋白产生免疫麻痹期间抗体与抗原的共存。
Immunology. 1966 Dec;11(6):571-88.
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