Aberg M, Bergentz S E
Eur Surg Res. 1979;11(4):282-8. doi: 10.1159/000128076.
Dextran infusion causes an increased lysability of ex vivo thrombi. This increased lysability is shown to be accompanied by a change in the distribution of 51Cr-labelled platelets. Rather than being localized to the head of the thrombus, after dextran infusion the platelets are found to be more evenly distributed. This change in platelet distribution is secondary to an effect of dextran on platelet function, probably via previously demonstrated impairment of the function of factor VIII. It is suggested that the increase in thrombus lysability is due to the change in platelet function.
右旋糖酐输注会导致离体血栓的溶解能力增强。这种增强的溶解能力表现为伴随着51Cr标记血小板分布的改变。输注右旋糖酐后，血小板并非局限于血栓头部，而是分布得更加均匀。血小板分布的这种变化是右旋糖酐对血小板功能影响的继发结果，可能是通过先前证实的对因子VIII功能的损害。提示血栓溶解能力的增强是由于血小板功能的改变。
