Paccagnella B, Ghezzo F, Prati L, Fedrazzoni U, Belloni G
Bull World Health Organ. 1971;45(2):181-99.
Two rural areas in Italy with different rates of pesticide usage were subjected to a cross-sectional investigation, based on the identification of organochlorine compounds in the environment and in human fatty tissues and on the determination of their concentration and a prospective investigation, based on the collection of data of past and present pathology and symptomatology from two stratified random groups of inhabitants of both areas.The cross-sectional investigation showed only small differences in environmental pollution and no differences in the storage of organochlorine compounds in fatty tissues in the two areas. The prospective investigation showed a higher prevalence of pathology and symptomatology in the population of the area where pesticides were used in larger quantities. Several haematochemical tests were used in an attempt to differentiate between populations at different levels of risk of toxic damage, but without success.
意大利两个农药使用量不同的农村地区接受了一项横断面调查，该调查基于对环境和人体脂肪组织中有机氯化合物的识别以及对其浓度的测定，还进行了一项前瞻性调查，该调查基于从两个地区分层随机抽取的两组居民收集过去和现在的病理及症状数据。横断面调查显示，两个地区在环境污染方面仅有细微差异，在脂肪组织中有机氯化合物的储存方面没有差异。前瞻性调查显示，农药使用量较大地区的人群中病理和症状的患病率更高。使用了几种血液化学测试来试图区分处于不同毒性损伤风险水平的人群，但未成功。
