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十二指肠溃疡中胃黏液的黏度。

Viscosity of gastric mucus in duodenal ulceration.

作者信息

Curt J R, Pringle R

出版信息

Gut. 1969 Nov;10(11):931-4. doi: 10.1136/gut.10.11.931.

DOI:10.1136/gut.10.11.931
PMID:5358586
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1553046/
Abstract

A preliminary study of the rheological behaviour of visible gastric mucus in patients with duodenal ulcer and in controls indicates that duodenal ulceration is associated with an increase in the viscosity of visible gastric mucus. The methods of measuring the viscosity of gastric mucin are described and the limitations of simple capillary viscometry are discussed. Several theories are advanced which may account for the findings described in this investigation.

摘要

对十二指肠溃疡患者和对照组可见胃黏液流变学行为的初步研究表明，十二指肠溃疡与可见胃黏液黏度增加有关。文中描述了测量胃黏蛋白黏度的方法，并讨论了简单毛细管黏度测定法的局限性。提出了几种理论来解释本研究中所描述的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36aa/1553046/00deda7211b1/gut00701-0072-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36aa/1553046/3f6de38fdcdc/gut00701-0071-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36aa/1553046/00deda7211b1/gut00701-0072-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36aa/1553046/3f6de38fdcdc/gut00701-0071-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36aa/1553046/00deda7211b1/gut00701-0072-a.jpg

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1
Viscosity of gastric mucus in duodenal ulceration.十二指肠溃疡中胃黏液的黏度。
Gut. 1969 Nov;10(11):931-4. doi: 10.1136/gut.10.11.931.
2
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本文引用的文献

1
STUDIES ON GASTRIC MUCUS IN HEALTH AND DISEASE. II. EVIDENCE FOR A CORRELATION BETWEEN ABO BLOOD GROUP SPECIFICITY, ABH(O) SECRETOR STATUS, AND THE FUCOSE CONTENT OF THE GLYCOPROTEINS ELABORATED BY THE GASTRIC MUCOSA.健康与疾病状态下胃黏液的研究。II. ABO血型特异性、ABH（O）分泌状态与胃黏膜分泌的糖蛋白中岩藻糖含量之间相关性的证据
Gastroenterology. 1965 Jun;48:758-67.
2
PROPERTIES OF GEL MUCIN OF HUMAN GASTRIC JUICE.人胃液凝胶黏蛋白的特性
Proc Soc Exp Biol Med. 1964 Jul;116:794-9. doi: 10.3181/00379727-116-29376.
3
The fucose and agglutinogen contents of saliva in subjects with duodenal ulcers.
天然胃肠道黏液：研究与药物、药物载体和细菌相互作用的关键特征和技术。
Adv Drug Deliv Rev. 2023 Sep;200:114966. doi: 10.1016/j.addr.2023.114966. Epub 2023 Jun 15.
4
The sorptivity and durability of gelling fibre dressings tested in a simulated sacral pressure ulcer system.在模拟骶部压疮系统中测试的凝胶纤维敷料的吸水性和耐久性。
Int Wound J. 2021 Apr;18(2):194-208. doi: 10.1111/iwj.13515. Epub 2020 Nov 25.
5
Acoustic radiation force optical coherence elastography for evaluating mechanical properties of soft condensed matters and its biological applications.用于评估软凝聚态物质力学特性的声辐射力光学相干弹性成像及其生物学应用
J Biophotonics. 2020 Mar;13(3):e201960134. doi: 10.1002/jbio.201960134. Epub 2020 Jan 2.
6
Micro- and macrorheology of mucus.黏液的微观和宏观流变学
Adv Drug Deliv Rev. 2009 Feb 27;61(2):86-100. doi: 10.1016/j.addr.2008.09.012. Epub 2009 Jan 3.
7
Helicobacter pylori infection does not reduce the viscosity of human gastric mucus gel.幽门螺杆菌感染不会降低人胃黏液凝胶的黏度。
Gut. 1995 Mar;36(3):327-9. doi: 10.1136/gut.36.3.327.
8
Effect of Helicobacter pylori on the gastric mucus gel.幽门螺杆菌对胃黏液凝胶的影响。
Gut. 1995 Aug;37(2):296. doi: 10.1136/gut.37.2.296.
9
The pathophysiology of duodenal ulceration.十二指肠溃疡的病理生理学
Gut. 1974 Jan;15(1):59-81. doi: 10.1136/gut.15.1.59.
10
Clinical significance of gastric juice viscosity in peptic ulcer patients.消化性溃疡患者胃液黏度的临床意义
Dig Dis Sci. 1988 Sep;33(9):1070-6. doi: 10.1007/BF01535780.
十二指肠溃疡患者唾液中的岩藻糖和凝集原含量。
J Lab Clin Med. 1960 Mar;55:386-99.
4
ABO blood groups and secretor character in duodenal ulcer; population and sibship studies.十二指肠溃疡中的ABO血型与分泌型特征；群体及同胞研究。
Br Med J. 1956 Sep 29;2(4995):725-31. doi: 10.1136/bmj.2.4995.725.
5
The viscometry of sputum.痰液粘度测定法
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6
The physiology of the gastric antrum; experimental studies on isolated antrum pouches in dogs.胃窦的生理学；对犬离体胃窦袋的实验研究。
Gastroenterology. 1954 Dec;27(6):766-85.
7
The blood groups in relation to peptic ulceration and carcinoma of colon, rectum, breast, and bronchus; an association between the ABO groups and peptic ulceration.血型与消化性溃疡以及结肠、直肠、乳腺和支气管癌的关系；ABO血型与消化性溃疡之间的关联。
Br Med J. 1954 Aug 7;2(4883):315-21. doi: 10.1136/bmj.2.4883.315.
8
Viscosity of cell-free canine gastric mucus.无细胞犬胃黏液的黏度
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