Kwiterovich P O, Sloan H R, Fredrickson D S
J Lipid Res. 1970 Jul;11(4):322-30.
An analysis of the lipids in normal human liver is presented which is particularly designed to assist in the classification and study of lipid-storage diseases. Special emphasis has been given to a determination of the quantity and composition of the neutral glycolipid classes and predominant ganglioside (Gm(3)). The neutral glycolipid content of 0.19 (sd +/- 0.11) micro moles per g wet tissue, represented 0.4% of the total lipid in liver. Ceramide dihexoside was the most abundant neutral glycolipid. The mean contents of cholesterol, glycerides, and total phospholipids were 3.9, 19.5, and 25.1 mg/g wet weight, respectively. The relative amounts of seven different phospholipid classes were also determined; these included cardiolipin (diphosphatidylglycerol), which constituted 3.9% of the liver phospholipids.
本文对正常人肝脏中的脂质进行了分析，该分析专门用于辅助脂质贮积病的分类和研究。特别着重于中性糖脂类和主要神经节苷脂（Gm(3)）的含量及组成的测定。每克湿组织中中性糖脂含量为0.19（标准差±0.11）微摩尔，占肝脏总脂质的0.4%。神经酰胺二己糖苷是最丰富的中性糖脂。胆固醇、甘油酯和总磷脂的平均含量分别为3.9、19.5和25.1毫克/克湿重。还测定了七种不同磷脂类的相对含量；其中包括心磷脂（二磷脂酰甘油），它占肝脏磷脂的3.9%。
