Jalan K N, Walker R J, Prescott R J, Butterworth S T, Smith A N, Sircus W
Gut. 1970 Aug;11(8):688-96. doi: 10.1136/gut.11.8.688.
The incidence of faecal stasis and of diverticular disease has been studied in a group of 399 patients with ulcerative colitis. Sixty-one patients had faecal stasis and 23 patients had diverticular disease. Pathological studies demonstrated an increase in the thickness of the inner spiral muscle in colitis patients with faecal stasis. The thickening was not as great as that seen in diverticular disease. Preliminary studies on the motility patterns in patients with faecal stasis show a higher mean activity in the pelvic colon than in normals but not as great as that seen in diverticular disease. Pressure studies in patients with faecal stasis have shown hypotonia in the proximal colon associated with dilatation.The possible significance of these results is discussed. It is suggested that ulcerative colitis may initiate a motility disturbance which leads to muscle thickening similar to that in diverticular disease. Diverticula associated with ulcerative colitis are usually not involved in the mucosal inflammatory process.
对一组399例溃疡性结肠炎患者的粪便淤积和憩室病发病率进行了研究。61例患者有粪便淤积，23例患者有憩室病。病理研究表明，有粪便淤积的结肠炎患者内螺旋肌厚度增加。增厚程度不如憩室病患者明显。对粪便淤积患者运动模式的初步研究显示，盆腔结肠的平均活动度高于正常人，但不如憩室病患者明显。对粪便淤积患者的压力研究表明，近端结肠张力减退并伴有扩张。讨论了这些结果可能的意义。有人提出，溃疡性结肠炎可能引发运动障碍，导致肌肉增厚，类似于憩室病。与溃疡性结肠炎相关的憩室通常不参与黏膜炎症过程。
