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[经典猪瘟中的病毒携带状态与病毒排泄]

[Viral carrier state and viral excretion in classical swine fever].

作者信息

Gamovski D, Vachev B, Motovski A, Enchev S

出版信息

Vet Med Nauki. 1979;16(10):24-7.

PMID:549263
Abstract

Studies on swine pest virus carrying and elimination on swine vaccinated by lapinizated vaccine strain "K" from rabbits were performed. Vaccinated swine were injected with the pathogenic virus on the 60th day post vaccination and to them were added not immunized swine with the aim to discover virus elimination. The experimental swine were decapitated on the 3, 5, 6 and 7th day post infection. Alternating passages were made by emulsion of the inner organs of these swine on not immunized swine as well as pathohistological investigation of the parenchymal organs and the brain. Presence of the virus and of pathohistological changes were not detected 7 days post injection of the virulent virus. Contact having swine which served as a indicator for virus elimination were observed for 21 days, but remained healthy. These swine, when infected with the virulent virus, suffered from pest.

摘要

对用兔化疫苗株“K”免疫的猪携带和清除猪瘟病毒的情况进行了研究。在接种疫苗后第60天给免疫猪注射致病病毒,并加入未免疫猪,以观察病毒清除情况。在感染后第3、5、6和7天对实验猪实施断头处死。用这些猪的内脏乳剂在未免疫猪上进行交替传代,并对实质器官和脑进行病理组织学检查。在注射强毒病毒7天后未检测到病毒存在和病理组织学变化。对作为病毒清除指示动物的接触猪观察21天,其保持健康。但这些猪在感染强毒病毒时会患猪瘟。

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