Traub W H, Raymond E A
Appl Microbiol. 1970 Oct;20(4):630-2. doi: 10.1128/am.20.4.630-632.1970.
Ninety clinical isolates of Pseudomonas aeruginosa were examined for susceptibility to carbenicillin by the broth dilution and disc diffusion methods. Inhibition zone diameters varied at given minimal inhibitory concentration levels of the antibiotic. Nevertheless, the results obtained allowed the proposal of the following tentative criteria for the interpretation of inhibition zones. Pseudomonadaceae yielding zones of inhibition measuring at least 10 and 16 mm in diameter around 25-and 100-mug discs, respectively, are sensitive to this antibiotic when examined by the standardized Bauer-Kirby method of disc susceptibility testing. Isolates characterized by zones of less than 100 mm in diameter around 25-mug discs should be tested with 100-mug discs before they are reported as sensitive or resistant to carbenicillin.
采用肉汤稀释法和纸片扩散法检测了90株铜绿假单胞菌临床分离株对羧苄青霉素的敏感性。在给定的抗生素最低抑菌浓度水平下，抑菌圈直径有所不同。然而，所获得的结果使得能够提出以下关于抑菌圈解释的初步标准。当通过标准化的鲍尔-柯比纸片药敏试验方法检测时，假单胞菌科在25微克和100微克纸片周围产生的抑菌圈直径分别至少为10毫米和16毫米，则对该抗生素敏感。在报告对羧苄青霉素敏感或耐药之前，对于在25微克纸片周围抑菌圈直径小于10毫米的分离株，应用100微克纸片进行检测。
