哈特曼氏变形虫（棘阿米巴）对5-氟胞嘧啶、羟乙磺酰苯脒及其他物质的敏感性。
Sensitivity of Hartmannella (Acanthamoeba) to 5-fluorocytosine, hydroxystilbamidine, and other substances.
作者信息
Casemore D P
出版信息
J Clin Pathol. 1970 Nov;23(8):649-52. doi: 10.1136/jcp.23.8.649.
Abstract
The effect of 24 anti-amoebic and other chemotherapeutic compounds on six strains of hartmannellid amoebae was studied by tissue culture, agar diffusion, and liquid axenic culture. Of the recognized anti-amoebic compounds only one inhibited growth of the amoebae, which were remarkable for their resistance. Two compounds, hydroxystilbamidine isethionate and 5-fluorocytosine, showed some amoebicidal activity while some others were inhibitory.
摘要
通过组织培养、琼脂扩散和液体纯培养研究了24种抗阿米巴及其他化疗化合物对6株哈特曼氏阿米巴的作用。在已确认的抗阿米巴化合物中，只有一种抑制了阿米巴的生长，这些阿米巴以其抗性而引人注目。两种化合物，羟乙磺酸羟乙脒和5-氟胞嘧啶，表现出一定的杀阿米巴活性，而其他一些则具有抑制作用。
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