Barnes I J, Bondi A, Fuscaldo K E
J Bacteriol. 1971 Feb;105(2):553-5. doi: 10.1128/jb.105.2.553-555.1971.
The genetics of lysine biosynthesis in Staphylococcus aureus was examined by a transductional analysis of lysine auxotrophs. These mutants had previously been grouped according to their biochemical characteristics. The mutant sites appeared to be closely linked. Complementation was observed between different groups but not between mutant strains belonging to the same group. A strain was detected which seemed to have a mutant control region. Evidence is presented to support the hypothesis that the lysine biosynthetic region functions as an operon.
通过对赖氨酸营养缺陷型菌株进行转导分析,研究了金黄色葡萄球菌中赖氨酸生物合成的遗传学。这些突变体先前已根据其生化特性进行了分类。突变位点似乎紧密连锁。在不同组之间观察到了互补作用,但在同一组的突变菌株之间未观察到。检测到一个似乎具有突变控制区的菌株。提供了证据来支持赖氨酸生物合成区域作为一个操纵子发挥作用的假说。