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维持性透析患者贫血的睾酮治疗

Testosterone therapy for anaemia in maintenance dialysis.

作者信息

Shaldon S, Koch K M, Oppermann F, Patyna W D, Schoeppe W

出版信息

Br Med J. 1971 Jul 24;3(5768):212-5. doi: 10.1136/bmj.3.5768.212.

Abstract

Intramuscular testosterone 250-500 mg weekly given to 25 patients on long-term haemodialysis produced a significant rise in haemoglobin level in all patients. The response was reversible when the drug was stopped. Treatment was effective in bilaterally nephrectomized patients and those with intact kidney tissue. The use of intramuscular testosterone is recommended for all adult patients on long-term haemodialysis in order to eliminate the need for routine blood transfusions.

摘要

对25例长期血液透析患者每周肌肉注射250 - 500毫克睾酮,所有患者的血红蛋白水平均显著升高。停药后反应可逆。该治疗方法对双侧肾切除患者和肾组织完整的患者均有效。建议对所有长期血液透析的成年患者使用肌肉注射睾酮,以避免常规输血的需要。

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