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用植物血凝素(PHA)培养淋巴细胞的正常人群剂量反应曲线的建立。

The establishment of a normal human population dose-response curve for lymphocytes cultured with PHA (phytohaemagglutinin).

作者信息

Fitzgerald M G

出版信息

Clin Exp Immunol. 1971 Mar;8(3):421-5.

Abstract

A dose-response curve was obtained for the stimulation by phytohaemagglutinin of lymphocytes of twenty-five normal human adults. Increase in the lymphocyte content of the culture (50–90%) produced an overall reduction of response which still fell within the normal limits. The curve is shown to be valuable in the routine investigation of patients with suspected immune deficiency.

摘要

获得了25名正常成年人淋巴细胞受植物血凝素刺激的剂量反应曲线。培养物中淋巴细胞含量增加(50%-90%)导致反应总体降低,但仍在正常范围内。该曲线在疑似免疫缺陷患者的常规检查中显示出价值。

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本文引用的文献

1
The variation in response of human peripheral lymphocytes to phytohemagglutinin in vitro.
Int Arch Allergy Appl Immunol. 1967;32(3):288-93. doi: 10.1159/000229939.
2
Mitogenic effect of phytohaemagglutinin at different ages.
Nature. 1967 Jul 8;215(5097):193-4. doi: 10.1038/215193a0.
3
Variation in the response of normal lymphocytes to PHA.
Int Arch Allergy Appl Immunol. 1969;35(2):105-18. doi: 10.1159/000230164.
4
5
Abnormalities of in vitro lymphocyte responses during rubella virus infections.
J Exp Med. 1968 Jul 1;128(1):47-68. doi: 10.1084/jem.128.1.47.
6
Technique and significance of lymphocyte transformation in allergic states.
Proc R Soc Med. 1970 Apr;63(4):349-50. doi: 10.1177/003591577006300409.
7
Immunological deficiency diseases.
Arch Pathol. 1968 Jul;86(1):95-107.
8
Lymphocyte transformation in diseases of lymphoid tissue.
Proc R Soc Med. 1970 Apr;63(4):355-7. doi: 10.1177/003591577006300411.
9
In vitro lymphocyte response in some immunity deficiency diseases and in intrauterine virus infections.
Proc R Soc Med. 1970 Apr;63(4):351-4. doi: 10.1177/003591577006300410.
10
The cellular basis of immunological responses. A synthesis of some current views.
Lancet. 1969 Aug 16;2(7616):367-71. doi: 10.1016/s0140-6736(69)92712-3.

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